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      community Pelage PP405 Phase 2a completed.

      in Research/Science  61 upvotes 2 months ago
      Minoxidil, finasteride, and RU58841 are discussed as treatments for hair loss, with excitement around a new drug, PP405, and a reformulated oral minoxidil in trials. Concerns about cost, side effects, and long-term use are also mentioned.

      community Topical rapamycin, metformin, a-kg grow hair

      in Research/Science  13 upvotes 5 years ago
      The conversation discusses the potential of topical rapamycin, metformin, and alpha-ketoglutarate (a-KG) for hair growth, with skepticism expressed about their effectiveness based on personal experience and existing use. It also mentions AICAR, known as cardarine or GW, which is not suitable for long-term use due to cancer risks in animal studies and its similarity to metformin.

      community Dutas and Minox results - mixed feelings

      in Finasteride/Dutasteride  239 upvotes 5 months ago
      A user experienced significant hair growth using oral dutasteride and minoxidil but developed severe erectile dysfunction, likely exacerbated by obesity and diabetes. They plan to lose weight and possibly adjust medication to alleviate side effects.

      community Azelaic acid with ru58841 combination

      in Treatment 2 months ago
      The conversation discusses using azelaic acid to reduce scalp inflammation while using RU58841 for hair loss. It suggests applying azelaic acid in the morning and RU58841 at night to avoid degradation, while also using dutasteride and minoxidil.

      community Dutasteride might be saving me

      in Progress Pictures  442 upvotes 7 months ago
      A user switched from finasteride to dutasteride due to side effects and saw significant hair improvement after 7 months, with no side effects from dutasteride. They also switched from topical to oral minoxidil, which may have contributed to the positive results.

      community Dut increase dose after year of no progress?

      in Finasteride/Dutasteride  5 upvotes 4 months ago
      The user has been on dutasteride and oral minoxidil for a year with no progress and is considering increasing the dutasteride dose or adding RU58841. Other users suggest consulting a doctor, trying derma needling with topical minoxidil, and note that hair loss treatments can have varying effectiveness.

      community Better Than Minoxidil? Topical Sodium Valproate

      in Research/Science  51 upvotes 1 year ago
      Topical sodium valproate may promote hair growth by inhibiting GSK3β, allowing beta-catenin to proliferate, but it has potential side effects and requires more research. The conversation also mentions skepticism about a product called Vdphlo1, which includes sodium valproate and other ingredients.

      community Quitting Alfatradiol after 4 months

      in Product  5 upvotes 1 year ago
      The user stopped using Alfatradiol after 4 months due to no hair improvement and side effects like dry scalp and gallbladder pain. They are considering trying topilutamide, which is suggested as an alternative.

      community Aevin hair creme, overwhelmingly positive feedback on website

      in Product  1 upvotes 11 months ago
      A user is considering trying Aevin hair creme, which contains ingredients like jojoba oil and saw palmetto, despite skepticism about its effectiveness compared to treatments like finasteride, minoxidil, or hair transplants. They are wary of the product's legitimacy due to the lack of reviews outside the brand's website.

      community Breezula - who tried CB0301/Clascoterone from gray marked/pharmas ?

      in Research/Science  1 upvotes 2 months ago
      The conversation discusses using CB0301/Clascoterone as a potential treatment for hair loss, especially for those experiencing side effects from finasteride and dutasteride. The user currently uses oral minoxidil and considers combining it with other treatments like kx826, DHT blocker supplements, and 2% Nizoral shampoo.

      community Approach: starting with dut then came om finestride

      in Finasteride/Dutasteride  2 upvotes 1 year ago
      The user initially used dutasteride, minoxidil, and vitamins, then switched to finasteride but experienced side effects and hair loss. They found better results with a natural supplement containing stinging nettle and beta-sitosterol, reporting thicker hair without side effects.

      community topical fluridil/eucapil + dut to block all DHT+T from scalp?

      in Treatment  7 upvotes 3 years ago
      User experienced slow gains with topical fin+min, switched to topical dut+min, and considered adding Eucapil. Another user suggested DUT may be less effective topically due to high molar mass and mentioned Fluridil as a weak anti-androgen that could help.

      community What happened to Pyrilutamide?

      in Technology  1 upvotes 1 year ago
      Pyrilutamide's 0.5% solution showed minimal improvement, while the 1% solution appears more promising but costly. The user is currently using finasteride and oral minoxidil and considering adding Pyrilutamide if effective and affordable.

      community Low-Dose Oral Minoxidil Does Not Significantly Affect BP

      in Minoxidil  178 upvotes 1 year ago
      Low-dose oral minoxidil is used for hair loss and does not significantly affect blood pressure but may increase heart rate and cause hypotensive symptoms. Some users experience side effects like palpitations and shortness of breath, while others find it effective; topical minoxidil with tretinoin is also considered.

      community Dutasteride High Libido. How come we don't talk about this?

      in Finasteride/Dutasteride  210 upvotes 1 year ago
      Dutasteride and finasteride can affect libido differently, with some experiencing increased libido and others decreased libido or erectile dysfunction. Dutasteride may increase testosterone levels but can also cause side effects like liver enzyme changes, while topical finasteride may have fewer sexual side effects.

      community Dutasteride mesotherapy - who has tried it?

      in Finasteride/Dutasteride  1 upvotes 1 year ago
      Dutasteride mesotherapy combined with topical minoxidil led to some hair regrowth, but taking dutasteride pills every 2-3 days showed more noticeable results. The user did not try finasteride, as their dermatologist recommended dutasteride for better outcomes with fewer side effects at a reduced dosage.

      community Oral dutasteride vs topical efficacy

      in Finasteride/Dutasteride  60 upvotes 1 year ago
      The user switched from topical minoxidil/dutasteride to oral dutasteride, resulting in hair loss. They resumed topical treatment without regrowth and are considering switching to finasteride due to poor results with oral dutasteride.

      community Chat is this real? Compound called clascoterone

      in Research/Science  588 upvotes 4 months ago
      Clascoterone shows promising results for hair regrowth in men with androgenetic alopecia, with potential FDA approval by 2026. It acts as a topical androgen receptor blocker, offering a new treatment option with minimal side effects compared to existing treatments like finasteride.

      community Dutasteride (.5mg) is some strong stuff!

      in Finasteride/Dutasteride  58 upvotes 4 years ago
      User switched from finasteride and minoxidil to dutasteride, experienced side effects, then took dutasteride once a week with improved hair density. Another user had success with daily dutasteride, while one had no results from topical dutasteride.