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    GlossaryWinlevi

    Winlevi, or clascoterone, is a topical medication approved for the treatment of acne and is being investigated for its potential use in addressing androgenetic alopecia, a common form of hair loss. It functions as an androgen receptor inhibitor, which means it can block the effects of androgens like dihydrotestosterone (DHT) that contribute to hair follicle miniaturization. Its relevance in hair biology lies in its ability to target the hormonal pathways involved in hair loss, offering a novel approach to treatment without the systemic side effects associated with oral medications. Key distinguishing characteristics include its topical application and its mechanism of action that specifically addresses androgen-related hair loss.

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      community Any one tried winlevi for hairloss?

      in Chat  4 upvotes 3 months ago
      Winlevi is being discussed as a potential treatment for hair loss. Users are sharing their experiences with Minoxidil, finasteride, and RU58841.

      community Winlevi (clascoterone) for hairloss?

      in Treatment  1 upvotes 10 months ago
      Winlevi (clascoterone), a DHT blocker, is being considered for hair loss treatment, though it's primarily an acne medication. Users discuss its potential effectiveness and note it may only work for a short time.

      community Using WinLevi (Clascoterone) for Seborrheic Dermatitis and Acne

      in Treatment  4 upvotes 2 years ago
      Winlevi (clascoterone) is discussed as a treatment for hormonal acne and seborrheic dermatitis due to its ability to block DHT and regulate sebum production. The post suggests that Winlevi could offer a novel approach for managing seborrheic dermatitis.

      community Winlevi coming out in 2019

       14 upvotes 7 years ago
      The conversation discusses the potential release of Winlevi in 2019 by Cassiopeia for hair loss treatment. It suggests a regimen combining minoxidil, Winlevi, Nizoral, and possibly dermarolling, with a comment mentioning Breezula as an alternative to finasteride without side effects.

      community Clascoterone (Winlevi) now approved in Canada

      in Product  14 upvotes 2 years ago
      The conversation is about the approval of Clascoterone (Winlevi) in Canada for hair loss treatment. One user expressed skepticism about its effectiveness due to low concentration.

      community Clascoterone (Winlevi) Update for Canada

      in Treatment  16 upvotes 3 years ago
      Clascoterone cream was submitted for review to Health Canada in August 2022, with hopes of approval within 3-6 months. It may potentially enhance finasteride's effects for hair loss treatment.

      community How to source winlevi? Not generica

      in Product  1 upvotes 2 weeks ago
      The conversation is about sourcing Winlevi (clascoterone) for personal use in the EU. The user is specifically looking for a non-generic version.

      community EMA is re-examining Winlevi (clascoterone at lower concentration)

      in Treatment  8 upvotes 10 months ago
      Clascoterone in Winlevi, a topical AR antagonist, is being re-examined due to concerns about HPA axis suppression in adolescents, but it's unlikely to be banned for adult use in androgenetic alopecia (AGA). The European Medicines Agency recommended refusing Winlevi for acne vulgaris, but this may not affect Breezula's approval for AGA.

      community When will WINLEVI be available?

      in Finasteride/Dutasteride  6 upvotes 5 years ago
      The conversation is about the availability of WINLEVI, a hair loss treatment, and the possibility of getting it compounded. The user is seeking information on when they can obtain the treatment.

      community FDA approves Cassiopea's WINLEVI (CB-03-01, 1% formulation) for Acne

      in Technology  34 upvotes 5 years ago
      The conversation is about the FDA approval of WINLEVI for acne treatment and the anticipation of Breezula, a hair loss treatment using the same active ingredient, which may indicate a positive future for Breezula's release. There is disappointment that Breezula's results are not optimal, but it is seen as progress in hair loss treatment.

      community cb-03-01 research chem (winlevi/clascoterone cream)

      in Technology  3 upvotes 2 years ago
      The user is considering using CB or clascoterone for hair loss, potentially as an alternative to RU. They're also contemplating asking a dermatologist for topical clascoterone cream to apply to their temple.

      community Clascoterone - clearnet vendor

      in Chat  2 upvotes 4 months ago
      The conversation is about finding a clearnet vendor for clascoterone, also known as Winlevi, for hair loss treatment. The user is seeking recommendations via direct message.

      community Whatever happened to breezula?

      in Finasteride/Dutasteride  16 upvotes 9 months ago
      Breezula, a potential hair loss treatment, is still in trials with no recent updates on its release, while its acne version, Winlevi, is available but expensive. Users discuss the high cost of hair loss treatments and alternatives like Minoxidil and topical Finasteride.

      community Disappointing news on Breezula/CB-03-01

       21 upvotes 7 years ago
      The conversation discusses disappointment over only receiving a financial report from Cassiopea instead of trial results for Breezula/CB-03-01, a hair loss treatment. However, there is optimism as the company is advancing Breezula into Phase III trials for men, starting trials for women, and submitting an NDA for their acne product, Winlevi.

      community Will you try clascosterone when it gets released?

      in Treatment  11 upvotes 2 months ago
      People are interested in trying clascosterone (Breezula) for hair loss, especially those who are too young for finasteride. Some users express concerns about the cost and prescription requirements, while others discuss alternatives like RU58841.

      community Clascoterone - Why are there so few posts if it’s already on the market?

      in Chat  34 upvotes 3 months ago
      Clascoterone is being discussed for hair loss, but its current acne formulation may not be suitable for scalp use due to potential skin irritation and lower dosage compared to Breezula. Users mention other treatments like finasteride, minoxidil, and pyrilutamide, with some expressing skepticism about clascoterone's effectiveness for hair loss.

      community Pyrludimide (KX-826) or Breezula (clascoterone)

      in Treatment  9 upvotes 1 month ago
      The conversation is about hair loss treatments, specifically Pyrludimide (KX-826) and Breezula (clascoterone), with the user unable to tolerate finasteride and dutasteride. The user plans to use these treatments alongside minoxidil, considering the efficacy and availability of each option.