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GlossaryWinlevi

Winlevi, or clascoterone, is a topical medication approved for the treatment of acne and is being investigated for its potential use in addressing androgenetic alopecia, a common form of hair loss. It functions as an androgen receptor inhibitor, which means it can block the effects of androgens like dihydrotestosterone (DHT) that contribute to hair follicle miniaturization. Its relevance in hair biology lies in its ability to target the hormonal pathways involved in hair loss, offering a novel approach to treatment without the systemic side effects associated with oral medications. Key distinguishing characteristics include its topical application and its mechanism of action that specifically addresses androgen-related hair loss.

Related Terms

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learn Clascoterone

a novel topical treatment that inhibits DHT on androgen receptors

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Research

5 / 14 results

research Clascoterone: First Approval

27 citations , October 2020 in “Drugs”

Clascoterone cream was approved in the USA for treating acne in people aged 12 and older.

research Androgens and acne: perspectives on clascoterone, the first topical androgen receptor antagonist

9 citations , April 2021 in “Expert opinion on pharmacotherapy”

Clascoterone is a new, effective, and safe acne treatment without systemic side effects.

research Androgen Receptor Inhibitors in the Treatment of Acne Vulgaris: Efficacy and Safety Profiles of Clascoterone 1% Cream

4 citations , July 2022 in “Clinical Cosmetic and Investigational Dermatology”

Clascoterone 1% cream is a promising new treatment for acne.

research Androgenetic Alopecia in Women: A Narrative Review of Pathophysiology, Clinical Evaluation, and Treatments

February 2026 in “American Journal of Clinical Dermatology”

Spironolactone is effective for treating female hair loss, with new treatments like clascoterone showing promise.

research TRADITIONAL AND ALTERNATIVE METHODS OF ACNE TREATMENT

May 2024 in “Aktualʹnì problemi sučasnoï medicini: Vìsnik Ukraïnsʹkoï medičnoï stomatologìčnoï akademì”

Spironolactone and clascoterone are promising acne treatments with fewer side effects.

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Community Join

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community Any one tried winlevi for hairloss?

in Chat 1 upvotes 2 months ago

Winlevi is being discussed as a potential treatment for hair loss. Users are sharing their experiences with Minoxidil, finasteride, and RU58841.

community Winlevi (clascoterone 1%) anyone trying it

in Treatment 2 upvotes 2 months ago

Winlevi (clascoterone 1%) is being discussed as a potential hair loss treatment. Users are considering its use despite concerns about its delivery method.

community Winlevi (clascoterone) for hairloss?

in Treatment 1 upvotes 8 months ago

Winlevi (clascoterone), a DHT blocker, is being considered for hair loss treatment, though it's primarily an acne medication. Users discuss its potential effectiveness and note it may only work for a short time.

community Using WinLevi (Clascoterone) for Seborrheic Dermatitis and Acne

in Treatment 4 upvotes 2 years ago

Winlevi (clascoterone) is discussed as a treatment for hormonal acne and seborrheic dermatitis due to its ability to block DHT and regulate sebum production. The post suggests that Winlevi could offer a novel approach for managing seborrheic dermatitis.

community Winlevi for 1 month on scalp. Testing it out so y’all don’t have to.

in Treatment 52 upvotes 2 years ago

A user is testing clascoterone (Winlevi) on their scalp for hair loss and has noticed a reduction in scalp sebum after one month. They are also using other unspecified treatments and plan to provide an update after the second month.

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