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      community Pelage Announces Positive Results of Phase 2a Trials for PP405

      in Update  300 upvotes 1 year ago
      PP405 shows promise in treating severe hair loss, with 31% of users experiencing over 20% hair density increase in four weeks, faster than minoxidil and finasteride. Some users are skeptical about the results' significance and long-term efficacy.

      community Genomic Sequencing for Hair Loss

      in Research/Science  156 upvotes 2 months ago
      Hair loss treatments like Minoxidil, finasteride, and potential mRNA therapies are discussed. There is skepticism about targeting specific genes due to the complex genetic nature of hair loss.

      community How much DHT causes hair loss ?

      in Finasteride/Dutasteride  2 upvotes 7 months ago
      The user is taking 2.5 mg dutasteride and 5% minoxidil but is not seeing hair regrowth, and is considering adding RU58841. They are experiencing fatigue and low MCV/MCH, possibly related to dutasteride, and are advised to be patient, consider microneedling, and check for iron deficiency.

      community new way to activate stem cells to make hair grow

       45 upvotes 7 years ago
      Stem cell-related treatments and drugs like RCGD423 and WAY are being tested for hair growth. Clinics are conducting tests on patients who haven't had previous treatments.

      community Blood work results concerning ?? Finasteride

      in Finasteride/Dutasteride  1 upvotes 1 year ago
      A 23-year-old male experienced nipple sensitivity after taking 0.5 mg finasteride for 2.5 months, with blood tests showing increased testosterone and estrogen levels. He stopped finasteride temporarily and seeks advice to prevent gynecomastia.

      community 10 months update - fin, min, derma stamp, RLT, keto shampoo

      in Progress Pictures  81 upvotes 5 months ago
      The user shared a 10-month hair loss treatment update using finasteride, minoxidil, derma stamping, red light therapy, and keto shampoo, reporting improved styling ability but a stubborn frontal hairline. The user experienced lower libido as a side effect of finasteride.

      community Latanoprost- an effective medication

      in Treatment  6 upvotes 4 months ago
      Latanoprost is discussed as a potential hair loss treatment, noted for its synergy with minoxidil and 5-AR inhibitors, but concerns include its effectiveness on scalp hair, cost, and potential skin darkening. Some users express interest in trying latanoprost or bimatoprost despite limited real-world evidence.

      community 3 month progress NW5 -- lost cause?

      in Progress Pictures  22 upvotes 3 years ago
      A user is treating their advanced hair loss with a regimen including topical finasteride, minoxidil, hydrocortisone, stem cell serum, peptide serum, multivitamins, he shou wu tea, derma pen, argan oil, and a derma roller. Replies suggest it's too early to judge progress and recommend staying consistent, with one suggesting oral minoxidil as an additional option.

      community Clascoterone (Winlevi) Update for Canada

      in Treatment  15 upvotes 3 years ago
      Clascoterone cream was submitted for review to Health Canada in August 2022, with hopes of approval within 3-6 months. It may potentially enhance finasteride's effects for hair loss treatment.

      community Today was Last update on pp405

      in Research/Science  109 upvotes 11 months ago
      A new hair loss treatment, PP405, is moving from phase 2A to 2B in clinical trials, sparking discussions about its potential to regrow dormant hairs and its impact on existing treatments like Minoxidil and finasteride. Some users express skepticism, while others are hopeful about its future effectiveness.

      community Topilutamide (fluridil) raw active?

      in Research/Science  7 upvotes 5 years ago
      Topilutamide is a potential hair loss treatment between Clascoterone and RU58841. Users discuss finding Topilutamide powder and its possible benefits for those who can't afford or tolerate other treatments.

      community 2Y 5M on dut, ask me anything

      in Finasteride/Dutasteride  130 upvotes 1 year ago
      A user experienced significant hair regrowth using dutasteride without side effects, starting with finasteride and not using minoxidil or dermarolling. They attributed success to a unique genetic response to DHT blockers but did not share their full regimen, frustrating others.

      community Most promising cures for baldness as of May 2026

      in Treatment  56 upvotes 4 weeks ago
      PP405 is the most promising future treatment for hair loss, aiming to reactivate dormant hair follicles. Clascoterone 5% is the most promising near-term drug, while current strategies include using finasteride or dutasteride to stabilize hair loss and minoxidil to stimulate growth.

      community 10 months fin 1mg - not much if any progress :/

      in Progress Pictures  80 upvotes 1 year ago
      The user has been using finasteride for 10 months with no significant regrowth but no further hair loss and is considering adding oral minoxidil despite concerns about side effects. Other users suggest combining finasteride with minoxidil for better results, as finasteride prevents further hair loss while minoxidil aids regrowth.

      community Ru-58841 or KX-826 (Pyrilutamide)?

      in Treatment  11 upvotes 3 years ago
      Exploring potential treatments for hair loss, with the focus being on comparing RU58841 and Pyrilutamide. Finasteride, Dutasteride, oral Minoxidil, microneedling, topical Minoxidil, Biotin, Zinc, Vitamin D and Nizoral are also discussed as part of a treatment stack.

      community After ten weeks of microneedling

      in Microneedling  154 upvotes 3 years ago
      A 39 year old male who has been balding since 23 and is intolerant to finasteride, using microneedling with Derminator 2 once per week and minoxidil foam twice daily in an effort to increase thickness of vellus hairs on the crown and maintain hairline.

      community Vicious male pattern baldness TINGLING ITCH!

      in Chat  9 upvotes 3 years ago
      A user struggles with male pattern baldness and a persistent tingling itch on their crown, trying various treatments like aloe vera, tea tree oil, and Nizoral without success. Another user suggests the itch might be psychosomatic, linked to worrying about hair loss.