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GlossaryCorneocytes

dead skin cells forming the outermost protective layer

Corneocytes are the dead, flattened cells that make up the outermost layer of the skin, known as the stratum corneum. They act as a protective barrier, preventing water loss and shielding the underlying living cells from environmental damage. For professionals, it's important to note that corneocytes are rich in keratin and are the end result of the keratinocyte differentiation process.

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research Protein profiling of forehead epidermal corneocytes distinguishes frontal fibrosing from androgenetic alopecia

March 2023 in “PLOS ONE”

Protein profiling of forehead skin can help distinguish between frontal fibrosing alopecia and androgenetic alopecia.

research Inherited Disorders of Corneocyte Proteins

11 citations , January 2010 in “Current problems in dermatology”

Ichthyoses are genetic skin disorders that affect the skin's barrier function.

Secreted Subtilisin Sub3 from Microsporum Canis Is Required for Adherence to but Not for Invasion of the Epidermis

research Secreted subtilisin Sub3 from Microsporum canis is required for adherence to but not for invasion of the epidermis

63 citations , November 2009 in “British journal of dermatology/British journal of dermatology, Supplement”

Sub3 is essential for fungus adherence but not for skin invasion.

research Fibre optic confocal imaging (FOCI) of keratinocytes, blood vessels and nerves in hairless mouse skin in vivo

36 citations , February 1998 in “Journal of Anatomy”

Fibre optic confocal imaging can visualize skin layers, blood vessels, and nerves in live mice.

Loss of Keratin K2 Expression Causes Aberrant Aggregation of K10, Hyperkeratosis, and Inflammation

research Loss of Keratin K2 Expression Causes Aberrant Aggregation of K10, Hyperkeratosis, and Inflammation

32 citations , April 2014 in “The journal of investigative dermatology/Journal of investigative dermatology”

Loss of keratin K2 causes skin problems and inflammation.

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