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research Epithelial barrier function: assembly and structural features of the cornified cell envelope

425 citations , August 2002 in “BioEssays”

The cornified cell envelope forms a protective barrier in skin and hair, using specific proteins and lipids to maintain effectiveness.

research Expression of epidermal keratins and filaggrin during human fetal skin development.

292 citations , October 1985 in “The Journal of Cell Biology”

Keratins and filaggrin change as fetal skin develops, marking key stages of skin formation.

research Conditional knock out of N-WASP in keratinocytes causes skin barrier defects and atopic dermatitis-like inflammation

27 citations , July 2017 in “Scientific Reports”

N-WASP is essential for healthy skin and preventing inflammation.

research Histologic Changes in the Skin of Hairless Mice Following Peeling With Salicylic Acid

74 citations , November 2000 in “Archives of Dermatology”

Salicylic acid can safely exfoliate and regenerate skin without causing inflammation.

research The Expression of Vitamin D-Upregulated Protein 1 in Skin and its Interaction with Sciellin in Cultured Keratinocytes

18 citations , September 2003 in “The journal of investigative dermatology/Journal of investigative dermatology”

VDUP1 is found in skin and hair follicles, interacts with sciellin, and may help regulate skin cell differentiation.

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community Topical tretinoin increases minoxidil absorption by 3x. Thoughts?

in Minoxidil 34 upvotes 7 years ago

Topical tretinoin can increase the absorption of minoxidil by three times, which may enhance its effectiveness for hair loss treatment. Tretinoin causes increased skin turnover, making the skin more permeable and potentially improving minoxidil's efficacy.

community I’m really tired of using minoxidil

in Minoxidil 42 upvotes 2 years ago

The user is frustrated with minoxidil's lack of results and is considering alternatives like oral minoxidil or finasteride despite concerns about side effects. Other suggestions include consulting a doctor, adjusting dosages, or considering a hair transplant.

community 17 month update 30M FUT 2300 grafts 1 year fin/min topical

in Progress Pictures 414 upvotes 2 years ago

A user shared a 17-month update on their hair loss treatment, which included a hair transplant of 2300 grafts, using a topical solution of minoxidil and finasteride, a laser cap, and ketoconazole shampoo. They are considering another transplant and seeking honest feedback on their progress, while others share their own experiences and advice on hair loss treatments.

community Hairloss has destroyed my Life completely

in Chat 339 upvotes 1 year ago

A young person is distressed about rapid hair loss despite using finasteride and recently starting oral minoxidil. Many suggest continuing treatment, considering dutasteride, and seeking therapy for mental health support.

community 3 months progress with Finasteride 0.5mg/daily, Minoxidil foam5% 2x daily, Stemoxydine 2x daily, Microneedling(M8) 1.5mm 1x per week, Saw Palmetto 400mg/day, peppermint and jojoba oils daily, Ketoconazole 2% shampoo 3x/week, Purador shampoo/conditioner every day.

in Progress Pictures 334 upvotes 3 years ago

Jordan-Iliad has been using a combination of finasteride, minoxidil, stemoxydine, microneedling, saw palmetto, peppermint and jojoba oils, ketoconazole shampoo, and Purador shampoo/conditioner for 3 months to treat their hair loss with stunning results. They have also recently started taking oral minoxidil 1.25mg/day in hopes of achieving even better results over the next 3 months.

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