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5 / 801 resultslearn Fluocinolone acetonide
learn SCUBE3
a signaling molecule from dermal papilla cells being actively researched
learn grandiflora extract
learn Vascular Endothelial Growth Factor
Research
5 / 1000+ resultsresearch Cortical cell types and intermediate filament arrangements correlate with fiber curvature in Japanese human hair
Hair curvature in Japanese people is linked to specific cell types and filament arrangements in the hair cortex.
research Effects of repeated exposure to ozonated water on hair fibre structure and integrity: Part I
This study examined the effects of repeated exposure to ozonated water on hair fibre structure and integrity. The results showed that ozonated water caused oxidative modifications in hair proteins, lipids, and pigments, leading to changes in structural, chemical, and functional properties. Specifically, there were increases in cysteic acid-related bands and carbonyl groups, indicating protein and lipid oxidation. Morphological changes included cuticle fusion and increased cortical fluorescence. Mechanical properties were affected, with increased denaturation temperature and post-yield stiffness, suggesting altered crosslink density and keratin disruption. Despite these changes, alterations in shine and colour were minimal. The study concludes that ozone exposure results in a unique damage signature affecting both the cuticle and cortex, warranting further investigation into lipidomic and biochemical changes and the hair's response to additional stressors.
research Cosmetic assessment of the human hair by confocal microscopy
Confocal microscopy is better than scanning electron microscopy for studying hair in its natural state and understanding hair products' effects.
research Acidic and basic hair/nail ("hard") keratins: their colocalization in upper cortical and cuticle cells of the human hair follicle and their relationship to "soft" keratins.
Hair and nail cells share similar proteins, indicating a common differentiation pathway.
research Stiffness of Human Hair Correlates with the Fractions of Cortical Cell Types
Hair stiffness is higher when it has more para-like cortical cells.
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5 / 1000+ resultscommunity If you were on finasteride, but experiencing negative symptoms and didn’t know about PFS, would you want someone to tell you?
Finasteride users discuss potential side effects, including Post Finasteride Syndrome (PFS), with varying opinions on its legitimacy and impact. Some users report side effects like changes in semen consistency and reduced pre-ejaculate, while others emphasize the rarity and reversibility of side effects.
community EU Shouldn't Ban Fin & Dut: PFS is NOT REAL.
Finasteride and Dutasteride do not cause depression or "Post Finasteride Syndrome," with concerns often linked to the nocebo effect and preexisting mental health issues. The EU is unlikely to ban these drugs, but access may become more restricted due to ongoing debates.
community Is this true? It can be a major breakthrough
Deoxyribose sugar gel may stimulate hair regrowth similarly to minoxidil by enhancing blood supply and follicle activity. Human trials are necessary, and current products have mixed results.
community Does someone like Prince William have such intense balding genetics that not even Dutasteride can save them?
Some men have strong balding genetics that treatments like Dutasteride, Minoxidil, or Finasteride may not fully address. Early intervention is believed to help, but many accept hair loss without treatment.
community Finasteride does deplete important nuero-active steroids
Finasteride can reduce neuroactive steroids, causing side effects like depression, anxiety, and sexual dysfunction. Some users experience persistent symptoms after stopping finasteride, while others use alternative treatments like topical solutions.