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Cyanidin 3-O-Arabinoside Suppresses DHT-Induced Dermal Papilla Cell Senescence by Modulating p38-Dependent ER-Mitochondria Contacts

research Cyanidin 3-O-Arabinoside Suppresses DHT-Induced Dermal Papilla Cell Senescence by Modulating p38-Dependent ER-Mitochondria Contacts

14 citations , March 2022 in “Journal of Biomedical Science”

Cyanidin 3-O-arabinoside may help treat a common form of hair loss by protecting cells against aging and improving cell function.

Cyanidin-3-O-Glucoside And Its Derivative Vitisin A Alleviate Androgenetic Alopecia By Exerting Anti-Androgen Effect And Inhibiting Dermal Papilla Cell Apoptosis

research Cyanidin-3-O-Glucoside And Its Derivative Vitisin A Alleviate Androgenetic Alopecia By Exerting Anti-Androgen Effect And Inhibiting Dermal Papilla Cell Apoptosis

December 2023 in “European Journal of Pharmacology”

C3G and Vitisin A may help prevent hair loss by blocking male hormones and stopping hair cell death.

research A Comprehensive Overview of Hibiscus Rosa-Sinensis and Its Uses: A Review

1 citations , May 2025 in “International Journal of Advanced Biochemistry Research”

Hibiscus rosa sinensis is beneficial for health due to its therapeutic properties and is generally safe.

research Several Selective Protein Kinase C Inhibitors Including Procyanidins Promote Hair Growth

32 citations , January 2000 in “Skin pharmacology and physiology”

Certain substances that block a specific protein help promote hair growth.

research Procyanidin Oligomers Counteract TGF-β1- and TGF-β2-Induced Apoptosis in Hair Epithelial Cells: An Insight into Their Mechanisms

14 citations , January 2006 in “Skin pharmacology and physiology”

Procyanidin compounds from apples and barley promote hair growth and prevent hair cell death.

View more "cyanidin" in research →

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4 / 4 results

community Aronia Chokeberry and Cyanidin 3-O-arabinoside for Hair Growth (AGA) Study

in Research/Science 14 upvotes 2 years ago

A natural compound called C3A from Aronia Chokeberry can help prevent hair loss by counteracting the effects of DHT. The user has been taking 50 grams of dried organic Aronia Chokeberry daily for 30 days and will update with photos in 60 days.

community Looks like a real cure to the root of baldness (DHT-induced senescence) was proven earlier this year

in Research/Science 732 upvotes 3 years ago

A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.

community What’s in Your 'Dream' Topical?

in Treatment 6 upvotes 7 months ago

The conversation discusses creating a personalized topical treatment for hair loss, with ingredients like finasteride, minoxidil, tretinoin, melatonin, caffeine, and others. Users share their ideal formulations, including combinations of minoxidil, finasteride, tretinoin, adenosine, and other compounds, while also discussing the importance of managing inflammation.

community Cell senescence-targeted treatment for hair loss, has anyone tried any products/enzymes etc. that use this theory

in Research/Science 5 upvotes 10 months ago

DHT causes hair loss by driving cells into senescence, and a polyphenol in black chokeberry may reverse this. A product using this theory is being considered for use alongside finasteride, minoxidil, and microneedling.