research WISP-1 Induced by Mechanical Stress Contributes to Fibrosis and Hypertrophy of the Ligamentum Flavum Through Hedgehog-Gli1 Signaling
Targeting Hedgehog signaling may help treat ligamentum flavum fibrosis.
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research Patched-Associated Tumors: Modifier Genes and Pathogenesis
The document concludes that the development of certain tumors is influenced by genetic background and that a specific gene modification can lead to tumor regression and reduced growth.
research P62 Pre-Clinical Pharmacological and Skin Penetration Profile of LDE255, a Novel and Specific Smoothened Antagonist
LDE225 is a promising skin-applied treatment for basal cell carcinoma with good skin penetration and effectiveness.
research Molecular Pathways Involved in Hair Follicle Tumor Formation: All About Mammalian Target of Rapamycin?
mTOR may link different pathways in hair follicle tumor formation.
research WISP-1 Induced by Mechanical Stress Contributes to the Fibrosis and Hypertrophy of Ligamentum Flavum via the Hedgehog-Gli1 Signaling
Mechanical stress causes ligament thickening through WISP-1 and Hedgehog signaling.
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