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GlossaryDermal Papillae

small skin projections crucial for hair growth and nutrient supply

Dermal papillae are small, nipple-like extensions of the dermis (the inner layer of the skin) that project into the epidermis (the outer layer of the skin). In the context of hair, they are located at the base of hair follicles and play a crucial role in hair growth by supplying nutrients and signaling molecules to the hair matrix cells, which are responsible for producing hair.

Related Terms

Research

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research Hair multiplication with dermal papilla like tissue containing human dermal papilla cells

June 2014 in “Biotechnology and Bioprocess Engineering”

Injecting lab-grown hair cells into the scalp can regrow hair.

research Maintaining Hair Inductivity in Human Dermal Papilla Cells: A Review of Effective Methods

35 citations , January 2020 in “Skin Pharmacology and Physiology”

The review concluded that keeping the hair-growing ability of human dermal papilla cells is key for hair development and growth.

research Cultured dermal papilla cells from androgen-dependent human hair follicles (e.g. beard) contain more androgen receptors than those from non-balding areas of scalp

124 citations , April 1992 in “Journal of Endocrinology/Journal of endocrinology”

Beard hair follicles have more androgen receptors than non-balding scalp hair follicles.

research Biological characterization of cultured dermal papilla cells and hair follicle regeneration in vitro and in vivo

24 citations , February 2006 in “Chinese Medical Journal”

Cultured dermal papilla cells can regenerate hair follicles and sustain hair growth.

Inhibition of Hair Growth by Testosterone in the Presence of Dermal Papilla Cells from the Frontal Bald Scalp of the Postpubertal Stumptailed Macaque

research Inhibition of Hair Growth by Testosterone in the Presence of Dermal Papilla Cells from the Frontal Bald Scalp of the Postpubertal Stumptailed Macaque

19 citations , January 1997 in “Endocrinology”

Testosterone can slow hair growth in adult monkeys, but a blocker called RU 58841 can counteract this and potentially help hair regrow.

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Community Join

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community Hair follicle dermal papilla exosomes

in Treatment 2 upvotes 1 year ago

The conversation discusses using hair follicle dermal papilla exosomes for hair loss treatment. It inquires about purchasing options for this treatment.

community Hair cloning and injection of dermal papilla cells coming as soon as 2023

in Technology 119 upvotes 4 years ago

Hair cloning and injection of dermal papilla cells are discussed, with skepticism about their availability by 2023. Users mention Minoxidil, finasteride, and hair transplants as current treatments.

community HairClone (UK) finally begins offering its Dermal Papilla Cell Hair Multiplication procedure to humans. In Guatemala.

in Technology 148 upvotes 5 months ago

HairClone is offering a Dermal Papilla Cell Hair Multiplication procedure in Guatemala, raising questions about its effectiveness and regulatory reasons for the location. Users express skepticism and curiosity about the treatment's success and potential costs.

community New Peer-Reviewed Publication Further Validates RepliCel's Use of Dermal Sheath Cup Cells to Treat Pattern Baldness - Paper entitled "Hair Follicle Dermal Stem Cells Regenerate the Dermal Sheath, Repopulate the Dermal Papilla, and Modulate Hair Type" published journal Developmental Cell

11 upvotes 11 years ago

community [Nov 2019] The peptide AC 2 isolated from Bacillus-treated Trapa japonica fruit extract rescues DHT (dihydrotestosterone)-treated human dermal papilla cells and mediates mTORC1 signaling for autophagy and apoptosis suppression

22 upvotes 6 years ago

A peptide from Japanese water chestnut fruit may help with hair loss by suppressing DHT's effect on hair follicle cell death, potentially serving as a finasteride alternative. The treatment's effectiveness and safety in humans remain uncertain.

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Learn

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learn SCUBE3

a signaling molecule from dermal papilla cells being actively researched

learn Hair Multiplication

extract, clone, and reinsert your own hair cells

learn Valproic acid

an anticonvulsant repurposed for hair loss via histone inhibition

learn Dexpanthenol

precursor of vitamin B5 with hair stimulating effects

learn KY19382

compound that activates Wnt/β-catenin to promote hair regrowth and create new hair follicles

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Clinics

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All 180 clinic results →

Experts

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