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GlossaryPapillary Dermis

uppermost dermal layer with blood vessels and nerve endings

The papillary dermis is the uppermost layer of the dermis, which is the thick layer of skin beneath the outer epidermis. It contains thin collagen fibers, small blood vessels, and nerve endings, playing a crucial role in supplying nutrients to the epidermis and regulating temperature. This layer also contributes to the skin's tactile properties and helps in wound healing.

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Research

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research Mechanical Stretching Can Modify the Papillary Dermis Pattern and Papillary Fibroblast Characteristics during Skin Regeneration

19 citations , February 2022 in “Journal of Investigative Dermatology”

Mechanical stretching can improve or hinder skin regeneration depending on duration.

research Lineage Identity and Location within the Dermis Determine the Function of Papillary and Reticular Fibroblasts in Human Skin

159 citations , September 2018 in “Journal of Investigative Dermatology”

Papillary and reticular fibroblasts have distinct roles and are influenced by their environment.

research The Dermis of Millivora Capenesis

February 2019 in “American International Journal of Humanities Arts and Social Sciences”

The dermis of Millivora Capenesis has two layers with various connective tissues, blood vessels, glands, and sensory structures.

3D Printing of Skin Equivalents with Hair Follicle Structures and Epidermal-Papillary-Dermal Layers Using Gelatin/Hyaluronic Acid Hydrogels

research 3D Printing of Skin Equivalents with Hair Follicle Structures and Epidermal‐Papillary‐Dermal Layers Using Gelatin/Hyaluronic Acid Hydrogels

18 citations , July 2022 in “Chemistry - an Asian journal”

Scientists created a 3D printed skin that includes hair and layers similar to real skin using a special gel.

research 174 Dermis-hair follicle communication: Extracellular microvesicles signaling for hair regeneration

June 2020 in “Journal of Investigative Dermatology”

Tiny particles from skin cells can help activate hair growth.

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Community Join

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community Vitamin C and hair growth PH levels

in Product 32 upvotes 4 years ago

The conversation is about using vitamin C and Magnesium L-Threonate for hair growth by reducing DHT binding to dermal papilla cells. The original post about vitamin C's pH levels and sebum control was possibly removed by a moderator.

community Finasteride and natural topicals

in Finasteride 6 upvotes 7 years ago

A user reported hairline regrowth after two weeks on a treatment including finasteride, peppermint and rosemary oils, emu oil, magnesium oil spray, apple cider vinegar, and dermarolling, while avoiding shampoos and conditioners. They believe DHT contributes to hair loss but also suggest follicle fibrosis is an issue.

community AGA responded to steroid shots? Biopsy wrong? Please help!

in Female 2 upvotes 2 years ago

A woman with AGA is using spironolactone, dutasteride, finasteride, oral minoxidil, bicalutamide, and anti-androgenic birth control but still experiences worsening hair loss. Steroid shots temporarily stop her hair shedding, leading her to question her biopsy results.

community Reducing Fibrosis in Hair Loss: Topical Pirfenidone

in Research/Science 60 upvotes 4 months ago

Topical pirfenidone is highlighted as an effective anti-inflammatory and anti-fibrotic treatment for hair loss, particularly in addressing perifollicular fibrosis, which may enhance the effectiveness of standard treatments like finasteride and minoxidil. The user also uses calcipotriol, MCT oil, ciclopirox shampoo, and benzoyl peroxide shampoo as part of their regimen.

community 3.5 months progress - oral dut 0.5mg and oral min 5mg - 26M

in Progress Pictures 143 upvotes 2 years ago

A user reports hair regrowth and thickening after 3.5 months using oral dutasteride (0.5mg) and oral minoxidil (5mg). They express gratitude for the information received from the community about hair loss treatments.

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