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research Clonal analysis of stem cells in differentiation and disease

11 citations , July 2016 in “Current Opinion in Cell Biology”

New techniques have enhanced our understanding of how stem cells function and the role of mutations in aging tissues, which may influence future cancer therapies.

Differentiation of Adipose-Derived Stem Cells by Stimulation with Extracellular Vesicles from Dermal Papilla Cells Activated with Osteogenic and Adipogenic Inducers

research Differentiation of Adipose Derived Stem Cells by Stimulating with Extracellular Vesicles Secreted from Dermal Papilla Cells Activated with Osteogenic and Adipogenic Inducers

September 2022 in “Institutional Repositories DataBase (IRDB)”

Adipose-derived stem cells can be transformed into hair-forming cells using specific extracellular vesicles, offering potential for hair regeneration therapies.

research Differentiation of Mouse Induced Pluripotent Stem Cells into a Multipotent Keratinocyte Lineage

101 citations , December 2010 in “The journal of investigative dermatology/Journal of investigative dermatology”

Scientists turned mouse stem cells into skin cells that can grow into skin layers and structures.

research Two Opposing Faces of Retinoic Acid: Induction of Stemness or Induction of Differentiation Depending on Cell-Type

41 citations , October 2019 in “Biomolecules”

Retinoic acid can either maintain stem cells or make them specialize, depending on the cell type.

research Differentiation of human hair follicle stem cells into endothelial cells induced by vascular endothelial and basic fibroblast growth factors

24 citations , November 2013 in “Molecular Medicine Reports”

Human hair follicle stem cells can become endothelial cells with certain growth factors, useful for vascular treatments.

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5 / 56 results

community NMN Promotes Cell Proliferation and Hair Growth by Reducing Oxidative Stress

in Research/Science 14 upvotes 2 years ago

NMN shows promise in promoting hair growth by reducing oxidative stress and weakening androgens. It may be a beneficial addition to hair loss treatments like Minoxidil and Finasteride.

community A stress hormone has been found to signal through skin cells to repress the activation of hair-follicle stem cells in mice

in Research/Science 32 upvotes 5 years ago

Stress can lead to hair loss by affecting hair-follicle stem cells, and this loss is harder to recover from if one has male pattern baldness (MPB). Treatments like finasteride and minoxidil are used to address hair loss, but stress-related hair loss differs from androgenic alopecia.

community TGF-Beta. Good or Bad? Help for treatment investment

in Treatment 12 upvotes 3 years ago

TGF-B affects hair growth, both causing stem cell division and death depending on amounts. Amplifica's treatment injects Scube3 to increase TGF-B for hair growth.

community New Hair Loss Cure: AMP-303 Is Back. It’s what PP405 should have been.

in Research/Science 5 upvotes 3 months ago

AMP-303 and AMP-601 are new hair loss treatments targeting dermal papilla cells, with AMP-303 showing early efficacy in transitioning vellus hairs to terminal hairs after one injection. Further clinical trials are planned, and these treatments are seen as promising due to their biologic approach and less frequent application compared to daily treatments.

community Looks like a real cure to the root of baldness (DHT-induced senescence) was proven earlier this year

in Research/Science 739 upvotes 3 years ago

A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.

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