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GlossaryDisease Activity

Disease activity refers to the current state and severity of a disease, particularly in the context of autoimmune conditions that can affect hair loss, such as alopecia areata. It is relevant to hair loss as it helps in assessing the progression or regression of the condition, guiding treatment decisions. Key distinguishing characteristics of disease activity include the presence of new hair loss patches, changes in existing patches, and the overall inflammatory response in the scalp. Monitoring disease activity is crucial for understanding the potential for hair regrowth and the effectiveness of therapeutic interventions.

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Clinical and Trichoscopic Patterns of Hair Loss in Systemic Lupus Erythematosus and Its Correlation with Systemic Lupus Erythematosus Disease Activity Index

research Clinical and Trichoscopic Patterns of Hair Loss in Systemic Lupus Erythematosus and its Correlation with Systemic Lupus Erythematosus Disease Activity Index (SLEDAI)

May 2018

Hair loss in SLE patients is mostly due to chronic telogen effluvium and is linked to moderate disease activity.

Studying the Disease Activity and the Degree of Internal Organ Damage in Systemic Lupus Erythematosus Patients in the Kazakh Population

research LP-159 Studying the disease activity and the degree of internal organ damage in systemic lupus erythematosus patients in the Kazakh population

July 2023

Higher disease activity in systemic lupus erythematosus is strongly linked to more internal organ damage.

research Can the Second to Fourth Digit Ratio (2D : 4D) Be a Marker to Determine Ankylosing Spondylitis Disease Activity?

3 citations , February 2019 in “Disease Markers”

The index to ring finger ratio may indicate disease severity in female ankylosing spondylitis patients, but not in males.

GPX4 mRNA Levels in Polymorphonuclear Neutrophils Are Negatively Correlated with Autoantibody Production, Disease Activity, and Lupus Alopecia in Systemic Lupus Erythematosus

research GPX4 mRNA levels in the PMNs are negatively correlated with autoantibody production, disease activity and lupus alopecia in SLE

April 2023 in “Research Square (Research Square)”

Lower GPX4 mRNA levels are linked to higher disease activity and symptoms in lupus patients.

research Lichen Planus Activity and Damage Index (LiPADI)–Creation of the Questionnaire

6 citations , December 2021 in “Journal of Clinical Medicine”

LiPADI is a useful tool for monitoring the severity and treatment of lichen planus.

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Community Join

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community Supposedly dairy contains precursors to DHT that are already 5a-reduced and convert to DHT independent of 5a-reductase inhibition

in Research/Science 24 upvotes 4 months ago

Dairy may contain DHT precursors that could affect hair loss and prostate health, with some users noting reduced hair shedding after eliminating dairy. Individual responses to dairy and DHT blockers vary, with some attributing hair health to diet changes and others seeing no impact.

community RU-58841 Lung Disease Possibility | Chest pain, "heart issues", etc

in Treatment 22 upvotes 2 years ago

Some users of RU-58841 report cardiovascular symptoms like heart palpitations and chest tightness, which may be linked to its metabolites causing lung disease. The safety of RU-58841 is uncertain due to lack of long-term data and concerns about product purity, especially from gray market sources.

community 57% increased chance of pattern hair loss independently associated with the consumption of sugary beverages in men (p<0.001).

in Research/Science 299 upvotes 2 years ago

Sugary beverages increase the risk of pattern hair loss in men by 57%, and type 2 diabetes is linked to female pattern hair loss. Reducing sugar intake and using treatments like finasteride and minoxidil may help manage hair loss.

community Is it possible for androgenic alopecia to begin at early adolescent years?

in Chat 70 upvotes 3 years ago

Hair loss can begin in early adolescence and cause mental anguish. Treatments mentioned include eating cruciferous vegetables, engaging in physical activity, and maintaining scalp hygiene.