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Vitamin D Receptor Is Required for Proliferation, Migration, and Differentiation of Epidermal Stem Cells and Progeny During Cutaneous Wound Repair

research Vitamin D Receptor Is Required for Proliferation, Migration, and Differentiation of Epidermal Stem Cells and Progeny during Cutaneous Wound Repair

46 citations , May 2018 in “The journal of investigative dermatology/Journal of investigative dermatology”

The vitamin D receptor is essential for skin stem cells to grow, move, and become different cell types needed for skin healing.

research Treatment of MSCs with Wnt1a-conditioned medium activates DP cells and promotes hair follicle regrowth

61 citations , June 2014 in “Scientific Reports”

Wnt1a-conditioned medium from stem cells helps activate cells important for hair growth and can promote hair regrowth.

research Dandruff lesional scalp skin exhibits epidermal T cell infiltration and a weakened hair follicle immune privilege

March 2024 in “International Journal of Cosmetic Science”

Dandruff is linked to increased T cells and weakened immune protection in hair follicles.

research Dermal papilla cells and melanocytes response to physiological oxygen levels depends on their interactions

7 citations , June 2021 in “Cell Proliferation”

Low oxygen levels improve the function of hair and skin cells when they are in direct contact.

research Dermal Papilla Cells and Melanocytes Response to Physiological Oxygen Levels Depends on Their Interactions

August 2020 in “Research Square (Research Square)”

Oxygen levels affect hair growth and color cells differently when they interact directly.

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Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

in Research 865 upvotes 1 year ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

community HairClone developing cell replacement treatments for Hair Loss

7 upvotes 7 years ago

HairClone is developing cell replacement treatments to rejuvenate and generate hair follicles, and has launched a crowdfunding campaign. A user expressed skepticism about the need for crowdfunding.

community Shiseido filed for this patent in May 2019. Let's get some big brain discussion on this.

4 upvotes 6 years ago

The conversation discusses a patent filed by Shiseido for cloning Dermal Papilla (DP) cells to treat hair loss. The method involves using viral vectors to maintain the cells' growth-inducing properties, differing from Replicel's approach with Dermal Sheath Cup (DSC) cells.

community Protac degradation of the androgen receptor in mice shows good efficacy and no systemic drug could be found

in Research/Science 47 upvotes 3 years ago

The efficacy of degrading the androgen receptor through dermal application in DP cells, a delivery system for topical drugs that involves dissolving microneedles, and rosemary oil as an alternative anti-androgen.

community Researchers working on ways to regenerate lost hair from stem cells identified a recipe for normal hair regeneration in the lab. “A method for cyclical regeneration of hair follicles from hair follicle stem cells and will help make hair follicle regeneration therapy a reality in the near future.”

in Research/Science 259 upvotes 5 years ago

Hair loss treatments like finasteride, minoxidil, and hair transplants have side effects and limitations. There is hope for future advancements in stem cell therapy and hair follicle regeneration, though skepticism about their effectiveness and timeline persists.

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