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GlossaryDrug Reaction with Eosinophilia and Systemic Symptoms

severe allergic reaction to medication causing rash and organ damage

Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) is a severe, potentially life-threatening hypersensitivity reaction to certain medications. It is characterized by a widespread skin rash, fever, swollen lymph nodes, and involvement of internal organs such as the liver, kidneys, and lungs. Eosinophilia, an elevated level of a type of white blood cell called eosinophils, is a hallmark of this condition. Early recognition and discontinuation of the offending drug are crucial for managing DRESS.

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research Drug reaction with eosinophilia and systemic symptoms and severe involvement of digestive tract: description of two cases

19 citations , June 2011 in “British Journal of Dermatology”

Severe digestive issues in DRESS need early endoscopy for better treatment.

research HHV-6A and HHV-6B in Drug-Induced Hypersensitivity Syndrome/Drug Reaction with Eosinophilia and Systemic Symptoms

2 citations , January 2014 in “Elsevier eBooks”

The document concludes that reactivation of herpesviruses, especially HHV-6, is linked to severe symptoms and complications in drug-induced hypersensitivity syndrome.

Baricitinib for Alopecia Universalis Following Drug-Induced Hypersensitivity Syndrome/Drug Reaction with Eosinophilia and Systemic Symptoms

research Baricitinib for Alopecia Universalis Following Drug-Induced Hypersensitivity Syndrome/Drug Reaction with Eosinophilia and Systemic Symptoms

June 2026 in “Eurasian Journal of Medicine”

Baricitinib effectively regrew hair in a woman with alopecia universalis after other treatments failed.

research 392 Hair loss after drug reaction with eosinophilia and systemic symptoms: A multicentric retrospective study

April 2023 in “Journal of Investigative Dermatology”

Some patients who had a severe drug reaction developed long-term hair loss.

Hair Loss After Drug Reaction With Eosinophilia and Systemic Symptoms: A Multicentric Retrospective Case Series

research Hair loss after drug reaction with eosinophilia and systemic symptoms (DRESS): A multicentric retrospective case series

2 citations , January 2023 in “Journal of Dermatology”

Some types of hair loss can continue for a long time after recovering from a severe drug reaction known as DRESS.

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