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GlossaryDyspigmentation

abnormal color changes in skin or hair due to melanin issues

Dyspigmentation refers to abnormal changes in the color of the skin or hair due to irregularities in melanin production or distribution. This can manifest as patches of skin that are either darker (hyperpigmentation) or lighter (hypopigmentation) than the surrounding areas, and can be caused by various factors including genetic conditions, inflammation, infections, or exposure to certain chemicals.

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research Cutaneous Sequelae After Burn Injury: Pruritus, Dyspigmentation and Malignancy—Mechanisms and Management

April 2026 in “IntechOpen eBooks”

Burn injuries can cause long-term itching, skin color changes, and cancer risks, needing personalized treatment.

Antroquinonol Exerts Immunosuppressive Effect on CD8+ T Cell Proliferation and Activation to Resist Depigmentation Induced by H2O2

research Antroquinonol Exerts Immunosuppressive Effect on CD8⁺ T Cell Proliferation and Activation to Resist Depigmentation Induced by H₂O₂

11 citations , January 2017 in “Oxidative medicine and cellular longevity”

Antroquinonol may help prevent skin depigmentation by suppressing certain immune cells.

research Therapeutic effects of topical Mycophenolate mofetil on hydroquinone-induced depigmentation in Guinea pigs and mice

August 2025 in “Annals of Medicine”

Mycophenolate mofetil may safely help restore skin color in depigmentation conditions.

research Depigmentation Treatment for Vitiligo

March 2018

Cryotherapy is the best depigmentation method for vitiligo but needs an expert to perform it.

research Chemically Induced Depigmentation of Skin and Hair

January 1990 in “Springer eBooks”

Some chemicals can permanently or temporarily remove color from skin and hair, which can be distressing and is not well-regulated in cosmetics.

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community Betamethasone dipropionate 0.05 (sernivo spray)

in General 76 upvotes 1 year ago

A user was prescribed betamethasone dipropionate spray for a receding hairline, which caused skin peeling and depigmentation. They stopped using it and are considering alternatives like BPC-157/TB-500 for healing.

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