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GlossaryEGFR inhibitors

block cell growth signals to treat certain cancers

EGFR inhibitors, also known as Epidermal Growth Factor Receptor inhibitors, are a class of drugs that block the activity of the EGFR, a protein on the surface of cells that helps them grow and divide. By inhibiting this receptor, these drugs can slow down or stop the growth of certain types of cancer cells that rely on EGFR for proliferation. They are commonly used in the treatment of cancers such as non-small cell lung cancer and colorectal cancer.

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Research

5 / 1000+ results

Classification and Management of Skin, Hair, Nail, and Mucosal Side Effects of Epidermal Growth Factor Receptor Inhibitors

research Classification and management of skin, hair, nail and mucosal side-effects of epidermal growth factor receptor (EGFR) inhibitors

138 citations , February 2007 in “European journal of cancer”

EGFR inhibitors often cause skin problems and other side effects, but these are usually reversible and can be managed to keep patients comfortable.

research Persistent hair growth during treatment with the EGFR inhibitor erlotinib

39 citations , March 2009 in “Dermatology Online Journal”

Erlotinib can cause persistent excessive hair growth.

Semiology of Skin Toxicity Associated with Epidermal Growth Factor Receptor Inhibitors

research Semiology of skin toxicity associated with epidermal growth factor receptor (EGFR) inhibitors

38 citations , February 2012 in “Supportive Care in Cancer”

Skin problems like acne, dry skin, and nail and hair changes are common in patients taking EGFR inhibitors.

research Cutaneous side-effects of EGFR inhibitors and their management.

38 citations , January 2011 in “PubMed”

EGFR inhibitors often cause skin issues like acne and dryness, which can be managed with specific treatments.

research Erosive Pustular Dermatosis of the Scalp-Like Eruption due to Gefitinib: Case Report and Review of the Literature of Alopecia Associated with EGFR Inhibitors

36 citations , January 2012 in “Dermatology”

Stopping gefitinib improved scalp condition in a woman with lung cancer.

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community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 42 upvotes 6 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

community Medications that cause extra hair growth

in Research/Science 123 upvotes 2 years ago

The post discusses the side effects of various drugs causing excess hair growth, questioning why only minoxidil is used in the hair loss industry. The conversation includes users sharing their experiences and concerns about potential side effects of these drugs, with some preferring baldness over potential health risks.

community Creatine is the opposite of minoxidil !

in Research/Science 315 upvotes 9 months ago

Creatine may counteract minoxidil's hair growth effects by closing potassium ATP channels, potentially leading to hair loss in predisposed individuals. Despite anecdotal reports, there is no conclusive evidence linking creatine to hair loss.

community Creatine Does Not Increase DHT And Does Not Cause Hair Loss - Randomized Controlled Trial

in Research/Science 311 upvotes 1 year ago

Creatine does not increase DHT levels or cause hair loss. Personal experiences vary, but scientific evidence shows no link between creatine and hair loss.

community Dutasteride broked my liver (maybe)

in Finasteride/Dutasteride 8 upvotes 3 years ago

A user shared their experience with high cholesterol, glucose, and potential metabolic syndrome after using Finasteride and Dutasteride for hair loss. They plan to improve their health with diet and exercise before considering medication.

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Learn

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learn Epidermal Growth Factor

learn Tofacitinib

a JAK inhibitor for alopecia areata and other autoimmune conditions

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