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Development of a Liquid Chromatography/Mass Spectrometry-Based Inhibition Assay for Screening Steroid 5-Alpha Reductase in Human and Fish Cell Lines

research Development of a Liquid Chromatography/Mass Spectrometry-Based Inhibition Assay for the Screening of Steroid 5-α Reductase in Human and Fish Cell Lines

3 citations , February 2021 in “Molecules”

A new method was created to test the effectiveness of Dihydrotestosterone (DHT) inhibitors, like finasteride and dutasteride, in human and fish cells. The results showed fish cells are more sensitive to these treatments, and dutasteride works better than finasteride in all tested cells.

research Precocious Pubarche in a 7-Year-Old Patient. A Case Report

November 2024 in “Revista de Investigación y Educación en Ciencias de la Salud (RIECS)”

A 7-year-old girl developed early pubic hair growth without other puberty signs, diagnosed as isolated premature pubarche.

research Endocrine and metabolic characteristics in polycystic ovary syndrome.

53 citations , April 2016 in “PubMed”

PCOS affects multiple organs and requires combined treatment with lifestyle changes, metformin, and oral contraceptives.

research Screening for diabetes in women with polycystic ovary syndrome

3 citations , March 2007 in “Canadian Medical Association Journal”

Women with PCOS should have an oral glucose tolerance test for effective diabetes screening.

research Hidradenitis suppurativa/Acne inversa: an endocrine skin disorder?

41 citations , June 2016 in “Reviews in endocrine and metabolic disorders”

Hidradenitis suppurativa may be related to hormones and patients often have metabolic disorders; more research is needed to understand this connection.

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community risks with finasteride and dutasteride

in Research/Science 141 upvotes 1 year ago

Finasteride and dutasteride have potential risks, including post-finasteride syndrome, but are commonly used for hair loss. RU58841, minoxidil, and needling are suggested as alternatives, though all treatments carry risks.

community Anyone else realize how many younger guys are balding?

in Chat 262 upvotes 1 year ago

Many younger men are experiencing hair loss due to genetics, diet, stress, and lifestyle changes. Treatments like finasteride and minoxidil are mentioned, with some users noting improvements.

community Finasteride/dut. causes NAFLD,IR,diabetes,kidney dysfunction is it correct.

in Finasteride/Dutasteride 139 upvotes 3 years ago

Hair loss discussion mentions treatments like Finasteride, Dutasteride, and Minoxidil. Users share experiences, side effects, and advice on using these treatments.

community Here are the results from my journey! I used saw palmetto tablets instead of Finasteride(I was afraid of using it), 5% Minoxidil spray and Derma Pen once a week 1.5mm.

in Progress Pictures 306 upvotes 2 years ago

The user shared their positive hair regrowth experience using saw palmetto tablets, 5% minoxidil spray, and a Derma Pen. The conversation debates the effectiveness of saw palmetto versus finasteride, with some advocating for natural treatments and others emphasizing the proven results of finasteride and minoxidil, often in combination with microneedling.

community I don’t understand this, is he equating taking Fin with being on HRT?

in Finasteride/Dutasteride 302 upvotes 11 months ago

The conversation is about using finasteride and testosterone replacement therapy (TRT) for hair loss and their role in gender-affirming care. It debates whether these treatments are considered hormone replacement therapy (HRT) and their implications for both cisgender and transgender individuals.

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