Some people have low sulfotransferase enzymelevels, affecting their response to minoxidil. Lifestyle factors, genetics, and diet, like MSM intake, might influence these enzymelevels.
Beta-sitosterol may inhibit 5-alpha reductase type 2 enzyme, potentially reducing DHT levels and promoting hair growth, similar to finasteride but possibly with fewer side effects. Its effectiveness and side effects compared to other treatments like saw palmetto and finasteride remain uncertain due to limited research.
The user experienced high liver enzymelevels, possibly due to topical finasteride or supplements, and decided to stop using finasteride while continuing minoxidil. After stopping finasteride and supplements, liver levels returned to normal, suggesting finasteride or supplements might have been the cause.
Minoxidil's effectiveness varies due to differences in sulfotransferase enzymelevels in the scalp, affecting people with conditions like ASD, liver disease, and androgenic alopecia. Treatments like topical tretinoin, microneedling, and using minoxidil sulfate instead of regular minoxidil can improve results for those with low enzymelevels.
Some people respond better to minoxidil due to higher enzymelevels converting it to its active form. Minoxidil helps with hair regrowth but doesn't prevent hair loss; finasteride and other DHT inhibitors are needed for that.