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GlossaryEx Vivo Culture

growing cells or tissues outside their original biological context

Ex Vivo Culture refers to the process of growing or maintaining cells, tissues, or organs outside of their original biological context, typically in a controlled laboratory environment. This technique allows researchers to study biological processes in a more natural state than in vitro (in a petri dish) while still being able to manipulate and observe the sample closely. For example, hair follicles can be cultured ex vivo to study hair growth and alopecia treatments.

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Research

5 / 1000+ results

research A simple method using ex vivo culture of hair follicle tissue to investigate intrinsic circadian characteristics in humans

12 citations , July 2017 in “Scientific reports”

Researchers developed a way to study human body clocks using hair tissue, which works similarly in both healthy and dementia patients.

research Ex Vivo Organ Culture of Human Hair Follicles: A Model Epithelial–Neuroectodermal–Mesenchymal Interaction System

13 citations , October 2010 in “Methods in molecular biology”

Hair follicle culture helps study cell interactions and effects of substances on tissue growth.

Human Hair Growth Ex Vivo Is Correlated With In Vivo Hair Growth: Selective Categorization of Hair Follicles for More Reliable Hair Follicle Organ Culture

research Human hair growth ex vivo is correlated with in vivo hair growth: selective categorization of hair follicles for more reliable hair follicle organ culture

27 citations , November 2005 in “Archives of Dermatological Research”

Choosing hair follicles at the same growth stage leads to more consistent hair growth experiments.

Prostaglandin F2α Stimulates Growth of Human Intermediate Hair Follicles in Ex Vivo Organ Culture with Potential Clinical Relevance

research Prostaglandin F2α stimulates the growth of human intermediate hair follicles in ex vivo organ culture with potential clinical relevance

June 2025 in “Frontiers in Physiology”

Prostaglandin F2α may help treat hair loss by promoting hair growth.

research Identification of human hair follicle antigens targeted in the presumptive autoimmune hair follicle disorder alopecia areata and their potential functional relevance in vitro : methods development for isolation and identification of alopecia areata-relevant human hair follicle antigens using a proteomics approach and their functional assessment using an ex vivo hair follicle organ culture model

January 2008 in “Bradford Scholars (University of Bradford)”

Alopecia areata may be caused by antibodies targeting specific hair follicle proteins, hindering hair growth.

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Community Join

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community Red Ginseng Extract Promotes the Hair Growth in Cultured Human Hair Follicles

18 upvotes 8 years ago

The conversation is about hair loss treatments, specifically discussing the effectiveness of Red Ginseng Extract in promoting hair growth. Other treatments mentioned include Minoxidil, finasteride, and RU58841.

community Weed/THC effects on hair growth/hair loss, and vitality of organ-culture human follicle studies (research review)

in Research/Science 4 upvotes 1 year ago

Cannabis and THC may have mixed effects on hair, with some studies suggesting potential negative impacts on hair growth in isolated hair follicles, but these results are hard to apply to living humans. Treatments like minoxidil and finasteride are commonly used for hair loss, and the effects of cannabis might be neutral or vary based on individual factors.

community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 42 upvotes 6 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

community P-1075: a BETTER version of Minoxidil

in Research/Science 9 months ago

P-1075 is a more potent hair growth agent than Minoxidil, but it poses significant heart risks, making it unsafe for use. Despite promising results in macaques, concerns about its cardiotoxicity in rats have halted its development.

community So we have 20k dollars human like machines available but no new effective treatment for hairloss since finasteride :)

in Chat 237 upvotes 1 year ago

There have been no new effective hair loss treatments since finasteride, despite technological advancements. Current treatments include finasteride, minoxidil, and RU58841, with ongoing challenges and potential future solutions in research.

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