11 citations
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August 2025 in “Journal of Periodontal Research” Over the past 30 years, autologous platelet concentrates (APCs) like platelet-rich plasma (PRP) and platelet-rich fibrin (PRF) have been developed to enhance healing by concentrating growth factors and cells. PRF, which eliminates anti-coagulants, has shown superior natural healing benefits, particularly in dentistry for procedures such as periodontal regeneration and sinus grafting. Beyond dental applications, PRF is effective in treating diabetic ulcers, joint pain, and in esthetic medicine. Recent advancements include horizontal centrifugation techniques and the development of extended-PRF (e-PRF) membranes, which extend membrane degradation up to 4 months, offering a new alternative to collagen membranes in dental procedures.
January 2025 in “Acta Clinica Croatica” Using platelet rich fibrin speeds up wound healing after revascularization.
13 citations
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June 2016 in “Journal of neurological surgery” Using L-PRF membranes for skull base surgery might help healing, but more research is needed.
March 2017 in “Open access journal of surgery” The document concludes that more standardized research is needed to fully understand and optimize the use of platelet-rich fibrin in regenerative medicine.
14 citations
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July 2021 in “Biomedicines” Platelet-rich treatments can help improve wound healing and tissue repair.