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research The Suppression Effects of Fat Mass and Obesity Associated Gene on the Hair Follicle-Derived Neural Crest Stem Cells Differentiating into Melanocyte by N6-Methyladenosine Modifying Microphthalmia-Associated Transcription Factor

4 citations , February 2023 in “International Journal of Stem Cells”

The FTO gene hinders stem cells in hair follicles from becoming pigment cells.

research Polycystic ovary syndrome is linked with the fat mass obesity (FTO) gene variants rs17817449 and rs1421085 in western Saudi Arabia

2 citations , October 2021 in “Bioinformation”

Certain gene variants are linked to a higher risk of polycystic ovary syndrome, hair loss, and obesity in women from western Saudi Arabia.

research Emerging nonmetabolic functions of skin fat

65 citations , January 2018 in “Nature Reviews Endocrinology”

Skin fat has important roles in hair growth, skin repair, immune defense, and aging, and could be targeted for skin and hair treatments.

research 583 RNA sequencing of immortalised balding and non balding DPCs identifies potential balding gene signatures

November 2022 in “Journal of Investigative Dermatology”

The research found specific genes that are more active in balding cells, which could be causing hair loss.

Evidence for Masculinization of Adipokine Gene Expression in Visceral and Subcutaneous Adipose Tissue of Obese Women With Polycystic Ovary Syndrome

research Evidence for Masculinization of Adipokine Gene Expression in Visceral and Subcutaneous Adipose Tissue of Obese Women With Polycystic Ovary Syndrome (PCOS)

58 citations , January 2013 in “The Journal of Clinical Endocrinology and Metabolism”

Obese women with PCOS show a male-like pattern in certain fat tissue gene expressions.

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community Has anyone used Dutanol or Dutaheal (Indian generic) or other dutasteride tablets?

in Finasteride/Dutasteride 6 months ago

People are discussing switching to Indian generic dutasteride tablets like Dutanol and Dutaheal due to cost concerns, with some users reporting positive results when taken with a high-fat meal. Users have shared experiences with different brands, noting varying effectiveness and side effects compared to finasteride.

community What can be the real reason of Finasteride SE ?

in Finasteride/Dutasteride 20 upvotes 1 year ago

Finasteride can cause side effects like erectile dysfunction and decreased libido, possibly due to increased estradiol from testosterone aromatization, especially in those with higher body fat. Side effects vary widely and may also be influenced by genetic factors or neurosteroid inhibition.

community Expert of Reddit. Is this the (real) cure?

in Question 8 years ago

The conversation discusses potential hair loss treatments, including methylating estrogen, losing body fat, and supplementing with vitamins A, K2, and D. It also mentions reducing exposure to environmental estrogenics, with skepticism about genetic factors being the primary cause of baldness.

community Puffy cheeks from lack of dht? Water retention? Estrogen?

in General 55 upvotes 9 months ago

Stopping finasteride may reduce water retention or alter fat distribution, leading to a leaner face. Hormonal changes, like reduced DHT or increased estrogen, could cause these effects.

community Hate how younger generation makes hair seem more important than it is

in Chat 152 upvotes 5 months ago

A 25-year-old man is worried about his girlfriend noticing his balding and is frustrated by society's focus on looks. He uses minoxidil, finasteride, and dutasteride for hair loss and considers being honest with her.

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