5 citations
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July 2023 in “World Journal of Stem Cells” The study developed an injectable hydrogel from antler reserve mesenchyme (RM) matrix (HARM) to enhance regenerative wound healing. Using a rat model with full-thickness cutaneous wounds, the hydrogel was applied both locally and topically, creating a fetal-like niche at the wound site. This niche increased the expression of fetal wound healing-related genes such as Collagen III and TGFβ3, while decreasing Collagen I, TGFβ1, and Engrailed 1, and also increased the number of stem cells, aiding in the regeneration of cutaneous appendages. The findings suggest that HARM could be a promising candidate for clinical use in regenerative wound repair.
72 citations
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July 2022 in “Frontiers in Systems Biology” Modern lifestyles harm beneficial microbes, affecting health.
September 2023 in “Current opinion in microbiology” Certain fungi protect skin health, but changes can allow harmful fungi to cause serious infections, needing more research for treatment and control.
35 citations
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August 2021 in “npj Regenerative Medicine” Fibroblasts, cells usually linked to tissue repair, also help regenerate various organs and their ability decreases with age. Turning adult fibroblasts back to a younger state could be a new treatment approach.
August 2024 in “Revista Científica Multidisciplinar Núcleo do Conhecimento” Malassezia restricta may be linked to intestinal diseases like Crohn's and ulcerative colitis.