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GlossaryG2 phase

part of cell cycle ensuring DNA is ready for division

The G2 phase is a part of the cell cycle that occurs after DNA replication (S phase) and before cell division (mitosis). During this phase, the cell checks for DNA damage and ensures all the genetic material has been accurately replicated, while also producing proteins and organelles needed for cell division. This phase is crucial for maintaining genetic stability and preparing the cell for successful division.

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Research

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research 12-Chloracetyl-PPD, a novel dammarane derivative, shows anti-cancer activity via delay the progression of cell cycle G2/M phase and reactive oxygen species-mediate cell apoptosis

18 citations , December 2016 in “European journal of pharmacology”

A new compound slows cancer cell growth and causes cell death by blocking cell cycle progression and increasing cell-damaging molecules.

research G2 stem cells orchestrate time-directed, long-range coordination of calcium signaling during skin epidermal regeneration

4 citations , October 2021 in “bioRxiv (Cold Spring Harbor Laboratory)”

G2 stem cells control calcium signaling for skin regeneration.

research Implication of microRNA regulation in para-phenylenediamine-induced cell death and senescence in normal human hair dermal papilla cells

8 citations , March 2015 in “Molecular Medicine Reports”

Hair dye ingredient PPD causes cell death and aging in human hair cells by altering microRNA levels.

research The local hypothalamic–pituitary–adrenal axis in cultured human dermal papilla cells

9 citations , June 2020 in “BMC Molecular and Cell Biology”

Stress hormone CRF can cause hair loss by affecting hair growth cells and hormones.

research Myristoleic Acid Promotes Anagen Signaling by Autophagy through Activating Wnt/β-Catenin and ERK Pathways in Dermal Papilla Cells

8 citations , February 2021 in “Biomolecules & therapeutics”

Myristoleic acid helps hair growth by boosting cell growth and recycling processes in hair follicle cells.

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community Minoxidil Response Bottlenecks: Why Sulfation and Transport Matter (And Where Tretinoin Fits In)

in Research 461 upvotes 1 year ago

Minoxidil's effectiveness is limited by the need for sulfation and proper transport to hair follicles, with tretinoin potentially enhancing its effects by promoting enzyme activity and keratinocyte differentiation. Tretinoin may improve minoxidil's response by boosting the expression of necessary enzymes and transporters.

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Hair Transplant
Clinic Phaselis | Plastic Surgery AntalyaAntalya · TR

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