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GlossaryGene Sequencing

process of determining the exact order of DNA nucleotides

Gene sequencing, also known as DNA sequencing or genetic sequencing, is the process of determining the exact order of nucleotides within a DNA molecule. This technique allows scientists to read the genetic information encoded in an organism's DNA, which is crucial for understanding genetic disorders, evolutionary biology, and personalized medicine.

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Research

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research Investigation of Transcriptional Gene Profiling in Normal Murine Hair Follicular Substructures Using Next-Generation Sequencing to Provide Potential Insights into Skin Disease

1 citations , February 2016 in “Cell Transplantation”

Hair follicles have a more inactive cell cycle than other skin cells, which may help develop targeted therapies for skin diseases and cancer.

research 583 RNA sequencing of immortalised balding and non balding DPCs identifies potential balding gene signatures

November 2022 in “Journal of Investigative Dermatology”

The research found specific genes that are more active in balding cells, which could be causing hair loss.

research Sequencing KRT71 as a candidate gene for hair shape variation in dromedary camels

January 2025 in “Kuwait Journal of Science”

KRT71 gene variants may influence camel hair shape but don't fully explain it.

research Integrating whole-genome re-sequencing and transcriptome data to reveal the molecular mechanism of TBX5 gene regulating feathered feet in Guangxi native chickens

2 citations , February 2025 in “Poultry Science”

TBX5 gene influences feathered feet in Guangxi chickens by affecting cell growth and movement.

research Whole genome sequencing analysis of alpaca suggests TRPV3 as a candidate gene for the suri phenotype

February 2024 in “BMC genomics”

The TRPV3 gene variant may cause the long-haired suri alpaca coat.

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Community Join

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community Genomic Sequencing for Hair Loss

in Research/Science 156 upvotes 4 months ago

Hair loss treatments like Minoxidil, finasteride, and potential mRNA therapies are discussed. There is skepticism about targeting specific genes due to the complex genetic nature of hair loss.

community I believe CRISPR-on & CRISPR-off is an ultimate CURE for baldness, unlike Hair Cloning or hair loss treatments.

in Research/Science 24 upvotes 5 years ago

The conversation discusses CRISPR-on & CRISPR-off as a potential cure for baldness, contrasting it with hair cloning and other treatments like Minoxidil, finasteride, and RU58841. It also mentions the potential of mRNA for gene expression control and the prioritization of gene editing for severe genetic conditions.

community My Theory Of Androgenic Alopecia

in Research/Science 20 upvotes 8 months ago

Hair loss is linked to cellular physiology and the IGF-1 to TGF-B1 ratio, not just androgen sensitivity. The theory lacks evidence, while finasteride and minoxidil are effective treatments.

community Journey against alopecia - Finasteride 3 month

in Progress Pictures 18 upvotes 4 years ago

A 26-year-old man from France started experiencing hair loss in September 2020 and began using finasteride in June 2021, reporting some improvement after three months without side effects. He plans to continue finasteride for a year before considering additional treatments like minoxidil or dermarolling.

community So we have 20k dollars human like machines available but no new effective treatment for hairloss since finasteride :)

in Chat 237 upvotes 1 year ago

There have been no new effective hair loss treatments since finasteride, despite technological advancements. Current treatments include finasteride, minoxidil, and RU58841, with ongoing challenges and potential future solutions in research.

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Clinics

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Hair Loss Treatments
Gene Lee Skin ClinicSan Diego, CA · US

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