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GlossarymRNA sequencing

technique to determine the sequence of messenger RNA molecules

mRNA sequencing, also known as mRNA-seq, is a technique used to determine the sequence of messenger RNA (mRNA) molecules in a sample. This method helps researchers understand which genes are being actively expressed in a cell or tissue at a given time, providing insights into cellular functions and disease mechanisms.

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research Canonical prolactin signaling and global mRNA expression in the skin of Holstein heifers carrying the SLICK1 allele of the prolactin receptor gene

1 citations , February 2025 in “Journal of Dairy Science”

The SLICK1 allele in Holstein heifers affects hair and immune traits without altering prolactin signaling.

research Identification of Potential miRNA–mRNA Regulatory Network Associated with Growth and Development of Hair Follicles in Forest Musk Deer

December 2023 in “Animals”

The research found genes and miRNAs that may control hair growth in Forest Musk Deer.

research Comparative Analysis of mRNA and miRNA Expression between Dermal Papilla Cells and Hair Matrix Cells of Hair Follicles in Yak

December 2022 in “Cells”

Different genes and pathways are active in yak skin and hair cells, affecting hair growth and immune responses.

research Application of lncRNA-miRNA-mRNA ceRNA network analysis in the treatment of androgenic alopecia.

1 citations , December 2022 in “PubMed”

The lncRNA LOXL1-AS1 may help diagnose and treat androgenic alopecia.

research The post-terminal differentiation fate of RNAs revealed by next-generation sequencing

January 2012 in “eScholarship (California Digital Library)”

Hair and nails contain stable RNA, useful for personalized medicine and screening.

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community Genomic Sequencing for Hair Loss

in Research/Science 156 upvotes 4 months ago

Hair loss treatments like Minoxidil, finasteride, and potential mRNA therapies are discussed. There is skepticism about targeting specific genes due to the complex genetic nature of hair loss.

community We already know how to permanently fix hair loss. The science is done. The only thing missing is the funding to run one experiment.

in Technology 613 upvotes 2 months ago

A permanent hair loss solution could involve reprogramming hair follicles to resist DHT using mRNA and siRNA. However, high costs, safety concerns, and the pharmaceutical industry's preference for ongoing treatments over one-time cures are major obstacles, with finasteride and minoxidil remaining standard treatments.

community I believe CRISPR-on & CRISPR-off is an ultimate CURE for baldness, unlike Hair Cloning or hair loss treatments.

in Research/Science 24 upvotes 5 years ago

The conversation discusses CRISPR-on & CRISPR-off as a potential cure for baldness, contrasting it with hair cloning and other treatments like Minoxidil, finasteride, and RU58841. It also mentions the potential of mRNA for gene expression control and the prioritization of gene editing for severe genetic conditions.

Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

in Research 865 upvotes 1 year ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

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