26 citations
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August 2019 in “Stem Cell Research & Therapy”
PBX1 helps hairstem cells grow and change by turning on certain cell signals and preventing cell death, which may be useful for hair regrowth treatments.
MCL-1 is important for hairfolliclestemcell survival, but its impact on human hair regrowth is unclear. Minoxidil and finasteride are the main treatments, with doubts about new discoveries leading to effective human solutions soon.
Microneedling may enhance hair regrowth by transferring stem cells to dormant follicles, improving the effects of minoxidil. Users discuss using microneedling with needle lengths around 1.5mm to stimulate hair growth.
PP405 is viewed skeptically, with some seeing it as overhyped and potentially ineffective compared to existing treatments like minoxidil and finasteride. While it shows some promise in activating dormant hairfollicles, many believe it won't replace hair transplants or significantly outperform current options.
Hair loss treatments like Minoxidil, finasteride, and potential mRNA therapies are discussed. There is skepticism about targeting specific genes due to the complex genetic nature of hair loss.