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GlossaryHair Medulla

innermost layer of a hair strand, often containing air spaces

The hair medulla is the innermost layer of a hair strand, often composed of soft, spongy cells that may contain air spaces. While its exact function is not fully understood, it is thought to contribute to the hair's overall strength and may play a role in the hair's ability to insulate. Not all hair types have a medulla, and its presence can vary between individuals and even among different hairs on the same person.

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Research

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research [Contribution to hair medulla study (author's transl)].

4 citations , January 1981 in “PubMed”

Hair medullary cells in mammals vary in complexity, with humans having more structured cells similar to inner root sheath cells.

research Characterization of Hair Follicles in Hirosaki Hairless Rats with Deletion of Basic Hair Keratin Genes. Enlarged Medulla, Loss of Cuticle and Long Catagen

3 citations , March 2009 in “Hirosaki University Repository for Academic Resources (Hirosaki University)”

Hirosaki hairless rats have sparse, twisted hair due to missing hair keratin genes.

research Hair Medulla and its variations in Doshaja Prakruti – An observational study

September 2025 in “International Journal of Ayurvedic Medicine”

Hair medulla patterns vary by Prakruti type, affecting hair strength.

research Faculty Opinions recommendation of The keratins of the human beard hair medulla: the riddle in the middle.

March 2010 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

Beard hair medulla cells have a unique and varied keratin pattern.

research ABO Blood Grouping of Non-medullated Scalp Hair Using Immunohistochemical Staining

January 2010 in “Nihon Hou Kagaku Gijutsu Gakkaishi”

The modified staining method can determine the ABO blood group of hair samples accurately.

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Community Join

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community Hair regrowth without drugs (99% natural) 25M

in Progress Pictures 423 upvotes 2 weeks ago

A user shared their experience with hair regrowth using supplements like NAC and DIM, and briefly using minoxidil with microneedling. They reported some improvement in hair density, but the community questioned the effectiveness compared to traditional treatments like finasteride.

community Hair doesn't grow past a certain length

in Treatment 2 upvotes 2 weeks ago

The user is experiencing hair that doesn't grow past a certain length despite using minoxidil and finasteride for male pattern baldness. Suggestions include trying dutasteride, microneedles, and ketoconazole shampoo.

community Hair loss at age of 21

in Basic Questions 37 upvotes 3 weeks ago

A 21-year-old is concerned about hair thinning and seeks advice. Treatments mentioned include Minoxidil, finasteride, and RU58841.

community Hair Transplant Issues & Hair Loss Medication Side Effects - Similar Experiences

in Basic Questions 187 upvotes 3 weeks ago

The user experienced long-term pain after an FUE hair transplant and is considering Kenacort injections for relief. They also reported brain fog, dizziness, and anxiety after stopping minoxidil and finasteride, and are currently using PRP, microneedling, and rosemary oil for hair maintenance.

community Hair Cloning In The Near Future?! Shocking Results!

in Satire 1 month ago

Hair cloning is humorously discussed as a future solution for hair loss. Minoxidil and finasteride are mentioned as current treatments.

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