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research The Hair Follicle Bulge: A Niche for Adult Stem Cells

19 citations , July 2011 in “Microscopy and Microanalysis”

The hair follicle bulge is an important area for adult stem cells involved in hair growth and repair, with potential for medical use needing more research.

research 14-3-3σ Is Required for Club Hair Retention

8 citations , March 2010 in “The journal of investigative dermatology/Journal of investigative dermatology”

The 14-3-3σ gene is essential for preventing hair loss.

research Loose anagen hair of childhood: The phenomenon of easily pluckable hair

85 citations , February 1989 in “Journal of The American Academy of Dermatology”

Children with loose anagen hair have easily pluckable hair due to root sheath problems, and it might improve without treatment.

research A rare pediatric case of loose anagen hair syndrome

January 2026

Loose anagen hair syndrome in children may improve with age, but treatment results vary.

Interest of Silybum Marianum Extract, Manganese PCA, and Lespedeza Capitata Extract in a New Anti-Hair Loss Serum to Stimulate Hair Growth and Prolong Anagen Phase

research 586 Interest of Silybum marianum extract, Manganese PCA and Lespedeza capitata extract in a new anti-hair loss serum to stimulate hair growth and prolong anagen phase

November 2022 in “Journal of Investigative Dermatology”

The extract of Silybum marianum, Manganese PCA, and Lespedeza capitata can boost hair growth and extend the growth phase when combined in a serum.

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Community Join

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community Nice product I discovered, thought I would share.

in Treatment 456 upvotes 1 year ago

A product that makes hair look thicker and healthier without promoting regrowth. Discussions include treatments like minoxidil, finasteride, red light therapy, and a serum with caffeine and peptides, with mixed effectiveness opinions.

community FDA Policy Shift Explained: What It Actually Means for PP405, VDPHL-01, Breezula and Hair Loss Drug Timelines

in Research/Science 42 upvotes 5 months ago

The FDA policy change may speed up approval for hair loss drugs like PP405, VDPHL-01, and Breezula by potentially eliminating the need for a second confirmatory Phase 3 trial. Approval timelines could be as early as 2028 for some treatments if Phase 3 results are strong.

community Microneedling must reach the stem cells in the upper hair shaft

in Treatment 79 upvotes 4 years ago

Microneedling should target depths of 0.5mm to 1.5mm for hair loss, with weekly sessions at 1mm recommended. Combining microneedling with Minoxidil is common for improved results.

community After using finasteride, did you notice an improvement in the hair shaft in terms of looking more “alive” and shiny?

in Finasteride/Dutasteride 2 upvotes 6 months ago

Finasteride users reported improvements in hair appearance, including increased thickness, shine, and darker color. Some users noticed their hair looked healthier and less sunburned after starting the treatment.

community Anyone shift to dut gel cap after tablet didn't work?

in Research/Science 1 upvotes 6 months ago

The user experienced worsening hair loss despite using dutasteride tablets and is considering switching to dutasteride gel capsules due to concerns about tablet bioavailability. Another user mentioned that countries like Japan, Korea, and India use the tablet form, suggesting the form may not be the issue.

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