3 citations
,
June 2021 in “Frontiers in genetics” The protein STAT3 slows down cell growth by blocking the FST gene, which affects hair development in sheep.
January 2021 in “Research Square (Research Square)” STAT3 reduces FST gene activity and cell growth, affecting hair development and wool quality.
January 2024 in “Animals” SP1 promotes and KROX20 inhibits hair cell growth by affecting the CUX1 gene.
September 2023 in “Animals” Hair follicle development in cashmere goats involves dynamic changes in proteins and metabolites, with key roles for oxytocin, MAPK, and Ca2+ pathways.
December 2025 in “Frontiers in Veterinary Science” This study investigated the gene expression profiles of hair follicles in newborn and one-year-old Qianhua Mutton Merino sheep to understand the molecular mechanisms of hair follicle development. Using transcriptome sequencing, 1,637 differentially expressed genes were identified, with significant enrichment in pathways like PI3K-Akt, MAPK, and Estrogen signaling. Key genes such as KRT27, IGF-2, FGF21, VEGF-D, KRT25, and KRT26 were highlighted as crucial for hair follicle development. The study found that the density of hair follicles decreased with age, while the S/P ratio increased. These findings provide a theoretical basis for understanding wool trait formation in these sheep.