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As a Carrier–Transporter for Hair Follicle Reconstitution, Platelet-Rich Plasma Promotes Proliferation and Induction of Mouse Dermal Papilla Cells

research As a carrier–transporter for hair follicle reconstitution, platelet-rich plasma promotes proliferation and induction of mouse dermal papilla cells

32 citations , April 2017 in “Scientific Reports”

Platelet-rich plasma can help grow more mouse hair follicles, but it doesn't work for human hair follicles yet.

research Poor Capability of 3D-Cultured Adipose-Derived Stem Cells to Induce Hair Follicles in Contrast to 3D-Cultured Dermal Papilla Cells

10 citations , January 2016 in “Annals of Dermatology”

3D-cultured dermal papilla cells are better at inducing hair follicles than adipose-derived stem cells.

No Differences in Stress Protein Induction and Proliferative Capability in Follicular Unit Grafts Obtained by Follicular Unit Excision and Follicular Unit Transplantation

research No Differences in Stress Protein Induction and Proliferative Capability in Follicular Unit Grafts Obtained by Follicular Unit Excision (FUE) and Follicular Unit Transplantation (FUT)

1 citations , March 2019 in “Hair transplant forum international”

Both hair transplant methods, FUE and FUT, show similar stress responses and growth abilities in hair cells.

research Inductive Properties of Hair Follicle Cells

68 citations , December 1991 in “Annals of the New York Academy of Sciences”

Hair growth can be induced by certain cells found at the base of hair follicles, and these cells may also influence hair development and regeneration.

research Hair matrix germinative epidermal cells confer follicle-inducing capabilities on dermal sheath and high passage papilla cells

61 citations , October 1996 in “Development”

Hair growth can be stimulated by combining certain skin cells, which can rejuvenate old cells and cause them to specialize in hair follicle creation.

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Community Join

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community HairClone developing cell replacement treatments for Hair Loss

4 upvotes 7 years ago

HairClone is developing cell replacement treatments to rejuvenate and generate hair follicles, and has launched a crowdfunding campaign. A user expressed skepticism about the need for crowdfunding.

community What Works to Restore Hairloss for Cis-Males? Not Much

in Treatment 18 upvotes 6 years ago

Hair regrowth treatments for cis-males include Minoxidil, Finasteride, and RU58841. Estrogen and testosterone blockers can help restore hair loss but may not suit everyone.

community Pelage Announces Positive Results of Phase 2a Trials for PP405

in Update 300 upvotes 1 year ago

PP405 shows promise in treating severe hair loss, with 31% of users experiencing over 20% hair density increase in four weeks, faster than minoxidil and finasteride. Some users are skeptical about the results' significance and long-term efficacy.

community Confused why people are calling PP405 a cure...it never claimed to be able to undo miniaturization or revert vellus back to terminal hairs. It seems to be more of a growth stimulant like minoxidil.

in Research/Science 55 upvotes 1 year ago

PP405 is not a cure for hair loss but may reactivate dormant hair follicles, similar to minoxidil. It is unlikely to help with miniaturized or vellus hairs and is still in trial phases, with availability expected around 2030.

community Proof that finasteride messes with neurosteroids

in Research/Science 230 upvotes 2 years ago

Finasteride can impact neurosteroids, potentially causing depression and other side effects in some users. Despite these concerns, many continue using it for hair loss, with some switching to topical applications to mitigate side effects.

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Learn

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learn Microneedling

technique to create small wounds in skin to activate collagen production and hair growth

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn KY19382

compound that activates Wnt/β-catenin to promote hair regrowth and create new hair follicles

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Clinics

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All 500 clinic results →

Experts

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