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GlossaryHLA-DR

protein on immune cells presenting antigens to trigger responses

HLA-DR is a part of the human immune system, specifically a protein found on the surface of certain cells that helps the body distinguish between its own cells and foreign invaders. It plays a crucial role in the immune response by presenting pieces of proteins (antigens) to immune cells, which can then trigger an immune reaction. This protein is also involved in autoimmune conditions, where the immune system mistakenly attacks the body's own tissues.

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research Immunogenetic and Metabolic Risk Factors in Male Androgenetic Alopecia: The Role of HLA-DRB1 Alleles and Vitamin D3 Deficiency

December 2025 in “Çukurova medical journal (Online)/Çukurova medical journal”

Certain genetic markers and low vitamin D3 levels are linked to male pattern baldness.

research Genetic Association of HLA-DQB1 and HLA-DRB1 Polymorphisms with Alopecia Areata in the Italian Population

35 citations , June 2011 in “British Journal of Dermatology”

The DQB1*03 allele is linked to higher alopecia areata risk in Italians.

research Exomic Sequencing of Immune-Related Genes Reveals Novel Candidate Variants Associated with Alopecia Universalis

18 citations , January 2013 in “PLoS ONE”

HLA-DRB5 and other genes may be linked to alopecia universalis.

research Human Leukocyte Antigen Class II Alleles Are Associated with Risk of Alopecia Areata

36 citations , July 2007 in “Journal of Investigative Dermatology”

Certain HLA class II alleles increase or decrease the risk of alopecia areata.

research Clinical and Genetic Aspects of Alopecia Areata: A Cutting Edge Review

1 citations , June 2023 in “Genes”

Hair loss from Alopecia Areata is caused by both genes and environment, with several treatments available but challenges in cost and relapse remain.

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community Dermastamping — do you use hyaluronic acid as lubricant?

in Microneedling 3 upvotes 1 year ago

The conversation discusses using high molecular weight hyaluronic acid after microneedling to form a protective barrier, though it's considered expensive and offers marginal improvement. Users share experiences with different microneedling tools like derma rollers, dermastamps, and Dr. Pen, with some opting not to use any products on the scalp.