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    GlossaryHairless Gene (HR gene)

    gene regulating hair growth, mutations cause permanent hair loss

    The Hairless Gene, often abbreviated as HR gene, is a gene that plays a crucial role in the regulation of hair growth and development. Mutations in this gene can lead to conditions such as congenital atrichia, where individuals are born with hair that is subsequently lost and not regrown, resulting in permanent hairlessness. This gene is essential for the normal cycling of hair follicles and the maintenance of hair.

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      PP405 Identity Research

      community PP405 Identity Research

      in Research  292 upvotes 4 months ago
      PP405 is a potential hair loss treatment that inhibits mitochondrial pyruvate carriers, increasing lactate dehydrogenase activity and stimulating hair follicle stem cells. In a phase 1 trial, 31% of participants showed over 20% hair density increase with PP405 treatment.

      community What regimen do I need to get this hairline?

      in Satire  362 upvotes 2 years ago
      Discussing a regimen to improve the user's hairline, with treatments proposed including minoxidil, rectal microneedling, IV drip of minoxidil, laser removal, PRP injection, topical minoxidil, divine protein shakes, stem cell injections, and keto shampoo.

      community Starting minoxidil and looking for a few tips

      in Minoxidil  7 upvotes 5 days ago
      The conversation is about using minoxidil for diffuse thinning after finasteride showed no regrowth. Tips include applying minoxidil directly to the scalp, considering potential shedding, and being cautious with combining tretinoin due to possible irritation.