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GlossaryHydrogen Bonds

weak attractions between hydrogen and electronegative atoms

Hydrogen bonds are a type of weak chemical bond that occurs when a hydrogen atom, which is covalently bonded to a more electronegative atom like oxygen or nitrogen, experiences an attraction to another electronegative atom nearby. These bonds are crucial in many biological processes, including the structure of DNA and the properties of water, and they play a significant role in the secondary and tertiary structures of proteins, including those found in hair.

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research Regulation of Receptor Binding Specificity of FGF9 by an Autoinhibitory Homodimerization

24 citations , July 2017 in “Structure”

FGF9 controls which receptors it binds to through a process where two FGF9 molecules join, and changes in FGF9 can lead to incorrect receptor activation.

research Characterisation of an Ovine Keratin Associated Protein (KAP) Gene, Which Would Produce a Protein Rich in Glycine and Tyrosine, but Lacking in Cysteine

24 citations , October 2019 in “Genes”

A new sheep gene, KRTAP36-1, may help breed sheep with better wool by reducing prickle factor.

research Chapter 4 Cytomechanics of Hair

19 citations , January 2009 in “International review of cell and molecular biology”

Hair's strength and flexibility come from its protein structure and molecular interactions.

research Influence of particle parameters on deposition onto healthy and damaged human hair

5 citations , August 2024 in “International Journal of Cosmetic Science”

Particles stick better to healthy hair than damaged hair.

research Mechanistic insights of desmopressin loaded elastic liposomes for transdermal delivery: HSPiP predictive parameters and instrumental based evidences

2 citations , November 2024 in “International Journal of Pharmaceutics X”

Desmopressin-loaded liposomes can effectively deliver drugs through the skin, improving bioavailability and patient compliance.

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community Is Pyrilutamide the real deal and if so when will it actually be available?

in Chat 21 upvotes 3 years ago

Pyrilutamide, a potential hair loss treatment that is currently in development and may be available soon; an androgen receptor degrader which is also being developed as a potential treatment for hair loss; and the comparison between Pyrilutamide, finasteride, minoxidil, and RU58841.

community Turmeric Inhibits Conversion of Testosterone to DHT; Creatine Enhances It - Kyle Gillett

in Research/Science 56 upvotes 4 years ago

Turmeric may slightly inhibit DHT, but it likely doesn't significantly impact hair loss. Creatine might increase DHT levels, but its effect on hair loss is debated and not conclusively proven.

community DHT Itch is real. The connection between Acne and Male Pattern Baldness shows this

in Research/Science 64 upvotes 2 years ago

The conversation discusses the link between seborrheic dermatitis, acne, and male pattern baldness, suggesting that DHT may cause both skin conditions and hair loss. Treatments mentioned include RU58841, finasteride, dutasteride, minoxidil, Nizoral shampoo, and other topical anti-androgens.

community When will FAK Inhibitors / Standford Hydrogel be on the market for hair transplants?

in Research/Science 8 upvotes 6 months ago

The conversation discusses the delay in bringing FAK inhibitors and Stanford's hydrogel to market for hair transplants, with a preference for FAK inhibitors over Verteporfin due to their superior potential in preventing scarring. The user expresses frustration over the slow progress and hopes for faster development by companies like FAKnostics.

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