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GlossaryHydrogen Bonds

weak attractions between hydrogen and electronegative atoms

Hydrogen bonds are a type of weak chemical bond that occurs when a hydrogen atom, which is covalently bonded to a more electronegative atom like oxygen or nitrogen, experiences an attraction to another electronegative atom nearby. These bonds are crucial in many biological processes, including the structure of DNA and the properties of water, and they play a significant role in the secondary and tertiary structures of proteins, including those found in hair.

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research Regulation of Receptor Binding Specificity of FGF9 by an Autoinhibitory Homodimerization

24 citations , July 2017 in “Structure”

FGF9 controls which receptors it binds to through a process where two FGF9 molecules join, and changes in FGF9 can lead to incorrect receptor activation.

research Characterisation of an Ovine Keratin Associated Protein (KAP) Gene, Which Would Produce a Protein Rich in Glycine and Tyrosine, but Lacking in Cysteine

24 citations , October 2019 in “Genes”

A new sheep gene, KRTAP36-1, may help breed sheep with better wool by reducing prickle factor.

research Chapter 4 Cytomechanics of Hair

19 citations , January 2009 in “International review of cell and molecular biology”

Hair's strength and flexibility come from its protein structure and molecular interactions.

research Influence of particle parameters on deposition onto healthy and damaged human hair

5 citations , August 2024 in “International Journal of Cosmetic Science”

Particles stick better to healthy hair than damaged hair.

research Mechanistic insights of desmopressin loaded elastic liposomes for transdermal delivery: HSPiP predictive parameters and instrumental based evidences

2 citations , November 2024 in “International Journal of Pharmaceutics X”

Desmopressin-loaded liposomes can effectively deliver drugs through the skin, improving bioavailability and patient compliance.

research Supramolecular insights into the complexation of β-Cyclodextrin for alopecia treatment using the mixed cation/anion active principle

May 2026 in “Carbohydrate Polymer Technologies and Applications”

The formulation effectively promotes hair growth with low systemic exposure.

research Essentials Of Trichophoric Designing

May 2013 in “International journal of innovative research and development”

The document concludes that understanding hair's chemical makeup is key to creating effective hair growth products that also improve social confidence.

research Learning from hair moisture sorption and hysteresis

4 citations , July 2022 in “International Journal of Cosmetic Science”

Hair moisture behavior helps tell apart different chemical treatments and reveals insights into hair structure.

Concentrated Conditioned Medium-Loaded Silk Nanofiber Hydrogels with Sustained Release of Bioactive Factors to Improve Skin Regeneration

research Concentrated Conditioned Medium-Loaded Silk Nanofiber Hydrogels with Sustained Release of Bioactive Factors To Improve Skin Regeneration

5 citations , September 2019 in “ACS Applied Bio Materials”

The hydrogel with bioactive factors improves skin healing and regeneration.

research Crystal Structure of 3-Oxo-4-Aza-5-Alpha-Androstone-17 β-Tert-Butyl Carboxamide with an O···H–(C, N) Acceptor Four-Center Hydrogen Bond

2 citations , December 2008 in “Journal of Chemical Crystallography”

The research shows that hydrogen bonds greatly affect the crystal structure of a Finasteride derivative.

research Multifunctional hydrogel based on oxidized sodium alginate and carboxymethyl chitosan delivers minoxidil loaded liposomes for the treatment of androgenetic alopecia

January 2026 in “International Journal of Biological Macromolecules”

The hydrogel improves hair growth treatment by enhancing drug delivery and promoting follicle repair.

research Novel PLCL nanofibrous/keratin hydrogel bilayer wound dressing for skin wound repair

6 citations , December 2022 in “Colloids and Surfaces B: Biointerfaces”

The new wound dressing promotes cell growth and healing, absorbs wound fluids well, and is biocompatible.

research Identification of neprilysin as a potential target of arteannuin using computational drug repositioning

January 2017 in “Brazilian Journal of Pharmaceutical Sciences”

Arteannuin might work against cancer and Alzheimer's by targeting neprilysin.

research Recent Advances in Biodegradable and Biocompatible Synthetic Polymers Used in Skin Wound Healing

4 citations , August 2023 in “Materials”

New synthetic polymers help improve skin wound healing and can be enhanced by adding natural materials and medicines.

research Computational Screening of Repurposed Drugs Targeting Sars-Cov-2 Main Protease By Molecular Docking

1 citations , September 2022 in “Sudan Journal of Medical Sciences”

Danoprevir, remdesivir, and saridegib may effectively inhibit SARS-CoV-2.

research Self-Assembled Berberine-Sinapic Acid Nanomedicine for Synergistic Chemotherapy

February 2026 in “Molecules”

BBR-SA nanomedicine is a safe and effective treatment for breast cancer.

Molecular Docking and Dynamics Analysis of Phytochemicals from Nutmeg Fruit on Androgen Receptor as Anti-Alopecia Therapy

research Molecular Docking and Molecular Dynamics Analysis of Phytochemical Compounds from Nutmeg Fruit (Myristica fragrans Houtt.) on Androgen Receptor (4K7A) as Anti-Alopecia Therapy

December 2025 in “Fullerene Journal of Chemistry”

Geranylgeraniol from nutmeg may effectively treat hair loss, similar to finasteride and better than minoxidil.

research In Silico Screening of DrugBank Compounds as Potential Inhibitors for Human Steroid 5α-Reductase 2 for Androgen-Related Diseases

December 2023 in “Biointerface Research in Applied Chemistry”

Stiripentol shows promise as a potential treatment for androgen-related diseases but needs more testing.

research Fidelity of the Human Mitochondrial DNA Polymerase

101 citations , September 2006 in “Journal of Biological Chemistry”

Human mitochondrial DNA polymerase makes very few errors, crucial for preventing degenerative diseases.

research In silico analysis of ethyl acetate Bruguiera gymnorhiza leaf extracts as an anti-inflammatory agent

4 citations , September 2024 in “Jurnal Pengolahan Hasil Perikanan Indonesia”

Bruguiera gymnorhiza leaf extracts show potential for developing anti-inflammatory drugs.

research Baicalin Against Androgenetic Alopecia: A Network Pharmacology Study

October 2025

Baicalin may effectively treat hair loss by inhibiting 5α-reductase.

research Crystal structure of steroid reductase SRD5A reveals conserved steroid reduction mechanism

July 2020 in “bioRxiv (Cold Spring Harbor Laboratory)”

The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.

Sprayable Supramolecular Hydrogel with Minimalism for Wilderness First Aid: Integration of Mechanical Performance and Biofunctionality

research Sprayable supramolecular hydrogel with minimalism for wilderness first aid: integration of mechanical performance and biofunctionality

March 2026 in “Collagen and Leather”

The hydrogel speeds up wound healing and fights bacteria, making it great for emergency use.

research Flutamide-Loaded Zein Nanocapsule Hydrogel, a Promising Dermal Delivery System for Pilosebaceous Unit Disorders

10 citations , June 2018 in “Aaps Pharmscitech”

The flutamide-loaded hydrogel is a promising, skin-friendly treatment for acne and hair loss, potentially requiring less frequent application.

Topical Application of Magnetized Saline Water Hydrogel Promotes Rapid Pressure Ulcer Healing in Hospitalized Elderly Patients: An Acute Care Case Series

research Topical Application of Magnetized Saline Water Hydrogel Promotes Rapid Pressure Ulcer Healing in Hospitalized Elderly Patients: An Acute Care Case Series

July 2025 in “Cureus”

Magnetized saline water hydrogel helps heal pressure ulcers quickly in elderly patients.

A Novel Point Mutation in the Ligand-Binding Domain of the Human Glucocorticoid Receptor Causing Generalized Glucocorticoid Resistance: The Importance of the C Terminus in Conferring Transactivational Activity

research A Novel Point Mutation in the Ligand-Binding Domain (LBD) of the Human Glucocorticoid Receptor (hGR) Causing Generalized Glucocorticoid Resistance: The Importance of the C Terminus of hGR LBD in Conferring Transactivational Activity

91 citations , May 2005 in “The Journal of Clinical Endocrinology & Metabolism”

A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.

research Androgen binding profiles of two distinct nuclear androgen receptors in Atlantic croaker (Micropogonias undulatus)

58 citations , June 2000 in “The Journal of Steroid Biochemistry and Molecular Biology”

Different types of androgens bind differently to two receptors, AR1 and AR2, in Atlantic croaker's brain and ovarian tissues, suggesting these receptors may control different androgen actions in fish.

Arctiin Blocks Hydrogen Peroxide-Induced Senescence and Cell Death Through MicroRNA Expression Changes in Human Dermal Papilla Cells

research Arctiin blocks hydrogen peroxide-induced senescence and cell death though microRNA expression changes in human dermal papilla cells

25 citations , September 2014 in “Biological Research”

Arctiin helps protect hair cells from damage and death caused by oxidative stress.

Candidate SNP Markers of Reproductive Potential Predicted by Significant Change in Affinity of TATA-Binding Protein for Human Gene Promoters

research Candidate SNP markers of reproductive potential are predicted by a significant change in the affinity of TATA-binding protein for human gene promoters

16 citations , February 2018 in “BMC Genomics”

Certain genetic markers linked to reproductive potential were identified by their impact on a protein's ability to bind to genes.

research Identification of microRNAs involved in growth arrest and cell death in hydrogen peroxide-treated human dermal papilla cells

12 citations , April 2014 in “Molecular Medicine Reports”

Targeting specific miRNAs may help treat hair follicle issues caused by hydrogen peroxide.