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GlossaryHydrogen Bonds

weak attractions between hydrogen and electronegative atoms

Hydrogen bonds are a type of weak chemical bond that occurs when a hydrogen atom, which is covalently bonded to a more electronegative atom like oxygen or nitrogen, experiences an attraction to another electronegative atom nearby. These bonds are crucial in many biological processes, including the structure of DNA and the properties of water, and they play a significant role in the secondary and tertiary structures of proteins, including those found in hair.

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research Crystal Structure of 3-Oxo-4-Aza-5-Alpha-Androstone-17 β-Tert-Butyl Carboxamide with an O···H–(C, N) Acceptor Four-Center Hydrogen Bond

2 citations , December 2008 in “Journal of Chemical Crystallography”

The research shows that hydrogen bonds greatly affect the crystal structure of a Finasteride derivative.

Chemical Bonds and Hair Behavior: A Review

research Chemical bonds and hair behaviour—A review

May 2024 in “International Journal of Cosmetic Science”

Disulfide bonds are crucial for hair's strength, especially when wet.

research Regulation of Receptor Binding Specificity of FGF9 by an Autoinhibitory Homodimerization

24 citations , July 2017 in “Structure”

FGF9 controls which receptors it binds to through a process where two FGF9 molecules join, and changes in FGF9 can lead to incorrect receptor activation.

research Structural characterization and dissolution profile of mycophenolic acid cocrystals

20 citations , February 2017 in “European journal of pharmaceutical sciences”

The MPA-ISO cocrystal improved solubility and dissolution rate, while the others did not.

research Chapter 4 Cytomechanics of Hair

19 citations , January 2009 in “International review of cell and molecular biology”

Hair's strength and flexibility come from its protein structure and molecular interactions.

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community Have you tried putting unconventional things on to your scalp ?

in Technology 3 upvotes 3 years ago

The conversation is about trying unconventional treatments for hair loss, such as green tea, coffee, cocoa, multivitamin pills, red wine, onion, honey, herbs, and hydrogen peroxide. The user is seeking feedback on these methods to avoid ineffective ones.

community Pyrilutamide update number 1 - 1 week use

in Update 55 upvotes 3 years ago

A user who is using Pyrilutamide, Finasteride, and a homemade topical solution to treat their hair loss. Replies mentioned the potential of Pyrilutamide being a "cure" for hair loss and a reminder that results may not be credited solely to it.

community Haircafe video on Min Sulfate, thoughts?

in Research/Science 101 upvotes 8 months ago

Minoxidil sulfate is considered for those unresponsive to regular minoxidil, with some trying a 10% formulation from Folligenz. Concerns exist about the product's stability and transparency, but some users report positive initial results.

community Dental technician is convinced that he has found the cause of pattern hair loss

in Research/Science 316 upvotes 1 year ago

A dental technician claims malocclusion causes pattern hair loss due to poor scalp circulation. Users debate this, noting treatments like finasteride, minoxidil, and microneedling focus on DHT and blood flow.

community When will FAK Inhibitors / Standford Hydrogel be on the market for hair transplants?

in Research/Science 8 upvotes 6 months ago

The conversation discusses the delay in bringing FAK inhibitors and Stanford's hydrogel to market for hair transplants, with a preference for FAK inhibitors over Verteporfin due to their superior potential in preventing scarring. The user expresses frustration over the slow progress and hopes for faster development by companies like FAKnostics.

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