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Complete Defect in PA-PLA1α Secretion Function Leading to Autosomal Recessive Woolly Hair and Hypotrichosis: Insights from a Novel Compound Heterozygous LIPH Variant Study in a Chinese Pedigree

research Complete defect in PA-PLA1α secretion function leading to autosomal recessive woolly hair and hypotrichosis: insights from a novel compound heterozygous LIPH variant study in a Chinese pedigree

May 2025 in “Frontiers in Genetics”

A new genetic variant in the LIPH gene causes hair growth issues in a Chinese patient.

research Hair Follicular Expression and Function of Group X Secreted Phospholipase A2 in Mouse Skin

35 citations , January 2011 in “Journal of Biological Chemistry”

sPLA2-X is crucial for normal hair growth and follicle health.

Food-Derived Crassostrea Gigas Peptides Self-Assembled Supramolecules for Scarless Healing

research Food-derived Crassostrea gigas peptides self-assembled supramolecules for scarless healing

2 citations , September 2022 in “Composites Part B: Engineering”

Pacific oyster peptides may help wounds heal without scars.

research From crown to cosmetics: Exploring the efficacy of an upcycled pineapple biopolymer in sustainable skincare, suncare and hair care applications

January 2026 in “International Journal of Cosmetic Science”

Upcycled pineapple biopolymer is effective and eco-friendly for skincare, suncare, and haircare.

research The β9 Loop Domain of PA-PLA1α Has a Crucial Role in Autosomal Recessive Woolly Hair/Hypotrichosis

11 citations , April 2012 in “Journal of Investigative Dermatology”

A specific mutation in PA-PLA1α causes abnormal hair growth.

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community Minoxidil Sulfate makes everyone a responder

in Research/Science 260 upvotes 1 year ago

Minoxidil sulfate is more effective than regular minoxidil, especially for those with low sulfotransferase levels or scalp sensitivity, but it is unstable unless delivered in a liposomal format. Combining minoxidil with tretinoin can enhance effectiveness, and stopping minoxidil use can lead to rapid hair loss.

community JXL082 is not PP405 and Everychem followed the wrong lead

in Research/Science 43 upvotes 11 months ago

JXL082 is not the same as PP405, leading to a halt in sales and a plan to synthesize the real PP405. There is skepticism about the safety and effectiveness of JXL082 and PP405, with concerns about patent issues and the long-term impact on hair growth.

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learn Hydrolyzed proteins

learn Hydrolyzed protein

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