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Imatinib mesylate can cause skin lightening, especially in Chinese patients, due to its effect on pigment production.

Melanocytes are destroyed by factors needed for melanin production, causing vitiligo and gray hair.

A girl grew extra hair in areas where she had insect bites.

Alopecia areata and psoriasis vulgaris can inhibit each other in the same areas.

Metformin may improve acanthosis nigricans by reducing insulin resistance.