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GlossaryHypogonadotropic Hypogonadism

condition where low hormone signals from the brain reduce sex hormone production

Hypogonadotropic Hypogonadism (HH) is a condition where the gonads (testes in men and ovaries in women) produce insufficient sex hormones due to a problem with the hypothalamus or pituitary gland, which are responsible for signaling the gonads to function. This can lead to delayed puberty, infertility, and other hormonal imbalances.

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research Sex Steroids, Precursors, and Metabolite Deficiencies in Men With Isolated Hypogonadotropic Hypogonadism and Panhypopituitarism: A GCMS-Based Comparative Study

46 citations , November 2014 in “The Journal of Clinical Endocrinology & Metabolism”

Men with isolated hypogonadotropic hypogonadism have partial steroid deficiencies, while those with panhypopituitarism have severe deficiencies.

Adult Onset Isolated Hypogonadotropic Hypogonadism: A Cause of Secondary Amenorrhea

research Adult Onset Isolated Hypogonadotropic Hypogonadism- a Cause of Secondary Amenorrhea

May 2021 in “Journal of the Endocrine Society”

A 23-year-old woman's missed periods were caused by a rare genetic disorder treated with hormone patches.

research Organic Causes of Erectile Dysfunction in Men Under 40

2152 citations , November 2013 in “Urologia Internationalis”

Many men under 40 with erectile dysfunction have organic causes like vascular issues, medication side effects, or hormonal problems.

Polycystic Ovary Syndrome and Its Differential Diagnosis

research Polycystic Ovary Syndrome and Its Differential Diagnosis

42 citations , January 2006 in “Obstetrical & Gynecological Survey”

The document concludes that correct diagnosis and management of PCOS are important, and more research is needed on its risks and treatments.

The Use of High-Density SNP Array to Map Homozygosity in Consanguineous Families to Efficiently Identify Candidate Genes: Application to Woodhouse-Sakati Syndrome

research The Use of High-Density SNP Array to Map Homozygosity in Consanguineous Families to Efficiently Identify Candidate Genes: Application to Woodhouse-Sakati Syndrome

7 citations , January 2015 in “Case reports in genetics”

Using SNP array testing helped quickly find the gene causing Woodhouse-Sakati syndrome in two related individuals.

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