July 2025 in “SVU-International Journal of Medical Sciences” Vitamin D-dependent rickets type II (VDDR-II) is a rare genetic disorder marked by resistance to vitamin D and severe cases of alopecia. This case report highlights a child's dental issues associated with VDDR-II, including sparse, hypoplastic teeth, profound dentin involvement, and delayed teething. Current treatments focusing on phosphorus and calcium supplementation may not adequately address dental abnormalities. A comprehensive, multidisciplinary management approach involving various specialists is essential for managing this complex condition in pediatric patients.
111 citations
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January 2007 in “Seminars in cell & developmental biology” Hair, teeth, and mammary glands develop similarly at first but use different genes later.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” Li2CO3 improved skin disease in a mouse model of Focal Dermal Hypoplasia without toxicity.
4 citations
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August 2016 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” Using cetirizine on the skin and taking vitamin D can help increase hair growth in children with hair loss from ectodermal dysplasia.
9 citations
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April 2020 in “Journal of dermatology” A person with a specific gene mutation had extra teeth, unique jaw and hair features not seen before in this condition.