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GlossaryImmune Dysfunction

immune system fails to protect the body properly

Immune Dysfunction, also known as Immune System Disorder, refers to a condition where the immune system does not function properly. This can manifest as an overactive immune response, leading to autoimmune diseases where the body attacks its own tissues, or an underactive response, resulting in immunodeficiency where the body is unable to effectively fight off infections. Examples include conditions like rheumatoid arthritis (autoimmune) and HIV/AIDS (immunodeficiency).

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Research

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The Interplay of Oxidative Stress and Immune Dysfunction in Hashimoto’s Thyroiditis and Polycystic Ovary Syndrome: A Comprehensive Review

research The interplay of oxidative stress and immune dysfunction in Hashimoto’s thyroiditis and polycystic ovary syndrome: a comprehensive review

1 citations , July 2023 in “Frontiers in Immunology”

Oxidative stress and immune dysfunction are linked to both Hashimoto's thyroiditis and polycystic ovary syndrome, with diet and specific treatments important for managing these conditions.

research 1368 Does mitochondrial dysfunction drive immune privilege collapse in lichen planopilaris pathogenesis?

April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology”

Mitochondrial dysfunction may contribute to chronic inflammation and immune system issues in Lichen planopilaris.

research Hidradenitis suppurativa: A folliculotropic disease of innate immune barrier dysfunction?

9 citations , August 2021 in “Experimental dermatology”

Hidradenitis suppurativa is a skin disease caused by the breakdown of the skin's natural immune barriers, especially around hair follicles.

research Clinical Application of Development of Nonantibiotic Macrolides That Correct Inflammation-Driven Immune Dysfunction in Inflammatory Skin Diseases

22 citations , January 2012 in “Mediators of inflammation”

Nonantibiotic macrolides show promise for treating various inflammatory skin conditions.

research Unraveling Vitiligo: From Immune Mechanisms to Promising Therapeutic Strategies

December 2024 in “Journal of Clinical Medicine of Kazakhstan”

Vitiligo treatments include JAK inhibitors, UVB phototherapy, and dietary changes, with emotional support being important.

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community Why is Finasteride seen as “scary” for men, but hormonal birth control is totally normalized for women?

in Finasteride/Dutasteride 757 upvotes 1 year ago

Finasteride is seen as risky for men due to side effects like erectile dysfunction, while hormonal birth control for women is normalized despite its side effects. The discussion points out a double standard influenced by societal and gender norms.

community How is dht not beneficial to you?

in Finasteride/Dutasteride 111 upvotes 5 months ago

DHT is important for sexual function and mood, but finasteride and dutasteride can reduce DHT, causing side effects like reduced libido and erectile dysfunction. These treatments are effective for hair loss, but their impact on DHT leads to debate.

community Finasteride does deplete important nuero-active steroids

in Research/Science 9 upvotes 2 years ago

Finasteride can reduce neuroactive steroids, causing side effects like depression, anxiety, and sexual dysfunction. Some users experience persistent symptoms after stopping finasteride, while others use alternative treatments like topical solutions.

community My Theory Of Androgenic Alopecia

in Research/Science 20 upvotes 8 months ago

Hair loss is linked to cellular physiology and the IGF-1 to TGF-B1 ratio, not just androgen sensitivity. The theory lacks evidence, while finasteride and minoxidil are effective treatments.

community You will lose hair if your prostaglandins aren't in balance

in Research/Science 56 upvotes 1 year ago

Prostaglandin balance affects hair loss, particularly in conditions like Lichen Planopilaris, where an imbalance can lead to hair follicle damage. Treatments mentioned include prostaglandin analogs and Pioglitazone HCL, with a focus on maintaining prostaglandin equilibrium for potential hair regrowth.

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learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

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