research Structure of human steroid 5α-reductase 2 with anti-androgen drug finasteride 4 citations , July 2020 in “Research Square (Research Square)” The research helps understand how finasteride works and aids drug development.
research In silico structural prediction of human steroid 5α-reductase type II 3 citations , March 2016 in “Medicinal Chemistry Research” Scientists found out the structure of a human enzyme linked to prostate cancer and hair loss, which could help in designing drugs.
research Structure of human steroid 5α-reductase 2 with the anti-androgen drug finasteride 30 citations , October 2020 in “Nature Communications” Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.
research HPLC Profiling and Insilco studies of Chochurus olitoris (Jute) Leave Fractions against Steroid 5α-Reductase 2 (SRD5α2) August 2024 in “Biomedical Journal of Scientific & Technical Research” Jute leaves may help reduce DHT levels, potentially aiding in conditions like hair loss and prostate issues.
research Crystal structure of steroid reductase SRD5A reveals conserved steroid reduction mechanism July 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.