research Tofacitinib: The selected selective JAK inhibitor in paediatric dermatology January 2024 in “International Journal of Dermatology Venereology and Leprosy Sciences” Tofacitinib may be safe and effective for treating certain skin conditions in children.
research 695 Selectively targeting JAK1 or JAK3 pathway is sufficient to reverse alopecia areata April 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” Blocking JAK1 or JAK3 helps reverse hair loss in a mouse model of alopecia areata.
research 170 Forecasting Phase 3 Dose-Response for Abrocitinib, an Oral Janus Kinase 1 Selective Inhibitor, Using Investigator’s Global Assessment and Eczema Area and Severity Index September 2019 in “Journal of Investigative Dermatology” Abrocitinib at 100 mg and 200 mg daily may significantly improve moderate-to-severe atopic dermatitis in patients 12 years and older.
research Selective inhibition of JAK3 signaling is sufficient to reverse alopecia areata 42 citations , April 2021 in “JCI insight” Blocking JAK3 signaling can reverse hair loss from alopecia areata.
research Sudden improvement of alopecia universalis and psoriatic arthritis while receiving upadacitinib: a case-based review 5 citations , October 2024 in “Reumatismo” Upadacitinib significantly improved alopecia universalis and psoriatic arthritis in a patient.
learn Baricitinib JAK inhibitor that reduces inflammation and immune attacks on hair follicles, leading to potential hair regrowth, especially in alopecia areata cases