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    GlossaryKeratinization Disorders

    abnormal keratin production causing skin, hair, and nail issues

    Keratinization disorders are conditions where the process of keratinization, the formation of the protein keratin in the skin, hair, and nails, is abnormal. This can lead to symptoms like thickened skin, scaling, and other skin abnormalities. Examples include psoriasis and ichthyosis, where the skin cells produce too much keratin or shed improperly, causing visible and sometimes uncomfortable skin changes.

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      Keratin Disorders: From Gene to Therapy

      research Keratin disorders: from gene to therapy

      109 citations , September 2011 in “Human molecular genetics online/Human molecular genetics”
      New treatments targeting specific genes show promise for treating keratin disorders.

      research Review of Keratin Disorders

      November 2019 in “Harper's Textbook of Pediatric Dermatology”
      Mutations in keratin genes cause skin, hair, and nail disorders, with future treatments possible.
      Keratin and Skin Disorders

      research KERATINS AND SKIN DISORDERS

      28 citations , April 1996 in “Cell biology international”
      Changes in keratin affect skin health and can lead to skin disorders like blistering diseases and psoriasis.

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