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    GlossaryLeucine-rich repeat-containing G-protein coupled receptor

    protein on cell surface involved in cell signaling

    Leucine-rich repeat-containing G-protein coupled receptors (LGRs) are a type of protein found on the surface of cells that play a crucial role in cell signaling. They are involved in various biological processes, including hormone regulation and development, by transmitting signals from outside the cell to the inside. These receptors are characterized by the presence of leucine-rich repeats, which are specific sequences of amino acids that help the receptor bind to its specific ligands.

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      community EMA is re-examining Winlevi (clascoterone at lower concentration)

      in Treatment  8 upvotes 9 months ago
      Clascoterone in Winlevi, a topical AR antagonist, is being re-examined due to concerns about HPA axis suppression in adolescents, but it's unlikely to be banned for adult use in androgenetic alopecia (AGA). The European Medicines Agency recommended refusing Winlevi for acne vulgaris, but this may not affect Breezula's approval for AGA.

      community DIY NutraKos-style 6–amino-acid mix (recipe + references)

      in Product  1 upvotes 1 month ago
      A user shared a DIY recipe for a NutraKos-style amino acid mix as a cost-effective alternative to the expensive product, suggesting it as a complementary supplement for hair loss. Another user argued that proven treatments like finasteride and minoxidil are more reliable, questioning the efficacy of the amino acid mix.

      community Indian Subcontinent specific : Fin effects

      in Finasteride/Dutasteride  6 upvotes 5 years ago
      Oral finasteride is recommended over topical finasteride for men in the Indian subcontinent, with no reported side effects. Minoxidil and dermarolling are also suggested, while dietary supplements and topical finasteride are deemed less effective.