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GlossaryLeucine-rich repeat-containing G-protein coupled receptor

protein on cell surface involved in cell signaling

Leucine-rich repeat-containing G-protein coupled receptors (LGRs) are a type of protein found on the surface of cells that play a crucial role in cell signaling. They are involved in various biological processes, including hormone regulation and development, by transmitting signals from outside the cell to the inside. These receptors are characterized by the presence of leucine-rich repeats, which are specific sequences of amino acids that help the receptor bind to its specific ligands.

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research Leucine-Rich Repeat-Containing G-Protein-Coupled Receptors as Markers of Adult Stem Cells

291 citations , April 2010 in “Gastroenterology”

Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.

research Tissue Engineering and Regeneration of the Human Hair Follicle in Androgenetic Alopecia: Literature Review

4 citations , January 2022 in “Life”

Tissue engineering could be a future solution for hair loss, but it's currently expensive, complex, and hard to apply in real-world treatments.

research Transcriptome Profiling and Differential Gene Expression in Canine Microdissected Anagen and Telogen Hair Follicles and Interfollicular Epidermis

7 citations , August 2020 in “Genes”

Different genes are active in dogs' hair growth and skin, similar to humans, which helps understand dog skin and hair diseases and can relate to human conditions.