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Did you mean Lymphocytic Inflammation?

GlossaryLymphocytic Inflammation

immune response where lymphocytes accumulate in tissue

Lymphocytic inflammation refers to a type of immune response where lymphocytes, a kind of white blood cell, accumulate in a particular tissue. This can occur in various conditions, including autoimmune diseases and infections, where the body's immune system targets its own cells or responds to pathogens. In the context of hair loss, such as in alopecia areata, lymphocytic inflammation can target hair follicles, leading to hair loss.

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research Perifollicular inflammation and follicular spongiosis in androgenetic alopecia

1 citations , September 2021 in “Journal of The American Academy of Dermatology”

Hair loss in both Androgenetic Alopecia and Alopecia Areata is often accompanied by inflammation around hair follicles, but the location and severity of this inflammation varies.

Topical Mechlorethamine Restores Autoimmune-Arrested Follicular Activity in Mice with an Alopecia Areata-Like Disease by Targeting Infiltrated Lymphocytes

research Topical Mechlorethamine Restores Autoimmune-Arrested Follicular Activity in Mice with an Alopecia Areata-Like Disease by Targeting Infiltrated Lymphocytes

19 citations , March 2003 in “Journal of Investigative Dermatology”

Mechlorethamine treatment regrew hair in mice by killing immune cells causing hair loss without harming hair follicles.

research Substance P in keratosis follicularis spinulosa decalvans

4 citations , September 2015 in “JAAD case reports”

Substance P may play a role in the inflammation seen in keratosis follicularis spinulosa decalvans.

research A Case of Inflammatory Nonscarring Alopecia Associated With the Tyrosine Kinase Inhibitor Nilotinib

16 citations , March 2013 in “JAMA Dermatology”

A cancer drug called nilotinib might cause hair loss due to inflammation around hair follicles.

research Frontal fibrosierende Alopezie – Fallbeispiele und Review

April 2021 in “Aktuelle Dermatologie”

Frontal Fibrosing Alopecia is a type of hair loss that mainly affects postmenopausal women, has unclear causes, and lacks evidence-based treatments.

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community DHT Harms Scalp Microbiome: DHT Itch is REAL

in Research/Science 416 upvotes 1 year ago

Increased Malassezia and Cutibacterium in the scalp microbiome are linked to higher sebum production and inflammation in androgenetic alopecia (AGA). Treatments include ciclopirox shampoo, benzoyl peroxide shampoo, clobetasol propionate, calcipotriol, minoxidil, finasteride, and dutasteride.

community Perifollicular Fibrosis and its role in androgenetic alopecia. Is Aminexil/Kopexil a must for anyone with AGA?

in Research/Science 4 upvotes 4 years ago

Aminexil/Kopexil may help reduce hair loss by addressing perifollicular fibrosis in androgenetic alopecia, but it lacks the extensive clinical backing of finasteride and minoxidil. Some users find it effective, but availability and cost are issues, especially in the US where it's not FDA-approved.

community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 1 year ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

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