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signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss
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Research
5 / 1000+ resultsresearch Discordant phenotype in monozygotic twins with mosaic trisomy 12p in lymphocytes
Identical twins had different symptoms because one had more cells with an extra chromosome fragment in different tissues.
research Hair follicle stem cell marker nestin expression in regenerating hair follicles of patients with alopecia areata
Nestin-positive cells are important for hair follicle regeneration in alopecia areata.
research Involvement of the bulge region with decreased expression of hair follicle stem cell markers in senile female cases of alopecia areata
Decreased CD200 in hair follicles may cause immune issues in some alopecia areata cases.
research Inflammatory perspectives of polycystic ovary syndrome: role of specific mediators and markers
PCOS is linked to inflammation, and certain markers could help in its treatment.
research Special Stains and Immunohistochemical Stains in Hair Pathology
Special and immunohistochemical stains are not routinely needed for diagnosing hair disorders.
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5 / 1000+ resultscommunity Dutasteride Isn't Working? Get a Scalp Biopsy NOW
Dutasteride may not be effective for everyone due to underlying issues, suggesting scalp biopsies for further diagnosis. Users discuss using higher doses of dutasteride, topical treatments, minoxidil, and pyrilutamide for hair loss management.
community I got my bloodwork done... What now?
The user has been experiencing hair thinning despite taking finasteride and minoxidil for six months. Bloodwork suggests a vitamin D deficiency, and users recommend consulting a doctor and possibly supplementing vitamin D.
community DHT Harms Scalp Microbiome: DHT Itch is REAL
Increased Malassezia and Cutibacterium in the scalp microbiome are linked to higher sebum production and inflammation in androgenetic alopecia (AGA). Treatments include ciclopirox shampoo, benzoyl peroxide shampoo, clobetasol propionate, calcipotriol, minoxidil, finasteride, and dutasteride.
community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied
Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.
community concerns about starting minoxidil
An 18-year-old woman experiencing hair loss due to stress, possible PCOS, and low vitamin D is concerned about starting 5% minoxidil foam, prescribed by her doctor, due to potential facial hair growth. She is also using a topical steroid for scalp sensitivity and pain.