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Did you mean Macrophage Polarization?

GlossaryMacrophage Polarization

process where immune cells change roles based on signals

Macrophage polarization refers to the process by which macrophages, a type of immune cell, change their functional state in response to different signals in their environment. They can adopt a pro-inflammatory state (M1) to fight infections or a healing state (M2) to repair tissues. This ability to switch roles is crucial for maintaining balance in the immune system and is important in conditions like infections, cancer, and autoimmune diseases.

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research Single-Cell RNA Sequencing Reveals Cellular and Transcriptional Changes Associated With M1 Macrophage Polarization in Hidradenitis Suppurativa

22 citations , August 2021 in “Frontiers in medicine”

Immune cells in Hidradenitis suppurativa become more inflammatory and may be important for treatment targets.

research Cedrol from Platycladus orientalis (L.) Franco regulates M1/M2 polarization of macrophages and promotes hair regeneration

January 2026 in “Journal of Ethnopharmacology”

Cedrol promotes hair growth better than baricitinib by regulating immune cells.

Human Adipose Tissue-Derived Small Extracellular Vesicles Promote Soft Tissue Repair Through Modulating M1-To-M2 Polarization Of Macrophages

research Human adipose tissue-derived small extracellular vesicles promote soft tissue repair through modulating M1-to-M2 polarization of macrophages

2 citations , April 2023 in “Stem Cell Research & Therapy”

Tiny fat-derived particles can help repair soft tissues by changing immune cell types.

research Intrinsic ROS Drive Hair Follicle Cycle Progression by Modulating DNA Damage and Repair and Subsequently Hair Follicle Apoptosis and Macrophage Polarization

20 citations , January 2022 in “Oxidative Medicine and Cellular Longevity”

Reactive oxygen species (ROS) influence hair growth by causing DNA damage, cell death, and changes in immune cells.

Sustained Exosome-Guided Macrophage Polarization Using Hydrolytically Degradable PEG Hydrogels for Cutaneous Wound Healing: Identification of Key Proteins and miRNAs, and Sustained Release Formulation

research Sustained Exosome‐Guided Macrophage Polarization Using Hydrolytically Degradable PEG Hydrogels for Cutaneous Wound Healing: Identification of Key Proteins and MiRNAs, and Sustained Release Formulation

40 citations , March 2022 in “Small”

Hydrogel with M2-derived exosomes improves wound healing by slowly releasing exosomes that help reduce inflammation and promote tissue repair.

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