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research SPRY1 Deficiency in Keratinocytes Induces Follicular Melanocyte Stem Cell Migration to the Epidermis through p53/Stem Cell Factor/C-KIT Signaling

4 citations , March 2024 in “Journal of Investigative Dermatology”

SPRY1 deficiency in skin cells causes stem cells to move to the skin surface, leading to increased pigmentation.

research Mechanisms of Hair Graying: Incomplete Melanocyte Stem Cell Maintenance in the Niche

January 2006 in “Yearbook of Dermatology and Dermatologic Surgery”

Hair graying is caused by the loss of pigment cells due to poor maintenance of stem cells in the hair follicle.

research Deficiency in Nucleotide Excision Repair Family Gene Activity, Especially ERCC3, Is Associated with Non-Pigmented Hair Fiber Growth

10 citations , May 2012 in “PloS one”

Low ERCC3 gene activity is linked to non-pigmented hair growth.

research Segmented Heterochromia in Black Scalp Hair Associated With Iron-Deficiency Anemia

18 citations , April 1989 in “Archives of Dermatology”

Iron deficiency can cause hair color changes, which can be reversed with iron supplements.

research Skin Hyperpigmentation and Increased Angiogenesis Secondary to Vitamin B12 Deficiency in a Young Vegetarian Woman

16 citations , January 2008 in “Acta dermato-venereologica”

Vitamin B12 deficiency can cause skin darkening and increased blood vessels, but treatment can improve symptoms.

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community Hormonal Imbalance Theory and the "Trash Hormone"...

in Research/Science 2 upvotes 3 years ago

Balancing hormones, particularly testosterone and DHT, may prevent hair loss and slow aging. Treatments include finasteride, dutasteride, zinc, magnesium, collagen, and natural DHT-blocking shampoos.

community Please explain this Minoxidil phenomena

in Minoxidil 58 upvotes 2 years ago

The post discusses the difference in effects of Minoxidil (Min) on scalp and facial hair. The user questions why Min-induced hair growth on the scalp is temporary, while facial hair growth seems permanent, even after stopping Min. They propose theories, including different Min mechanisms on body and facial hair, the role of DHT, and the possibility of not achieving fully terminal hair. The responses include personal experiences and theories about Min's effects on hair growth.

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learn Stem Cell Factor

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Melanogray

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