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GlossaryMelanocyte

cell producing melanin, pigment for skin, hair, eyes

A melanocyte is a type of cell found in the skin, eyes, and hair follicles that produces melanin, the pigment responsible for the color of your skin, hair, and eyes. These cells play a crucial role in protecting the skin from harmful UV radiation by absorbing and dissipating it. In conditions like vitiligo or certain types of alopecia, the function or presence of melanocytes can be disrupted, leading to changes in pigmentation.

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research Sox9 regulates melanocytic fate decision of adult hair follicle stem cells

10 citations , May 2023 in “iScience”

Sox9 is crucial for hair follicle stem cells to become melanocytes instead of glial cells.

research Tfap2b specifies an embryonic melanocyte stem cell that retains adult multi-fate potential

June 2021 in “bioRxiv (Cold Spring Harbor Laboratory)”

The gene Tfap2b is essential for creating a type of stem cell in zebrafish that can become different pigment cells.

research Gene expression profiling gets to the root of human hair follicle stem cells

92 citations , December 2005 in “The Journal of clinical investigation/The journal of clinical investigation”

Human hair follicle stem cells can be isolated using specific markers for potential therapeutic use.

research Do Hair Bulb Melanocytes Undergo Apotosis During Hair Follicle Regression (Catagen)?

130 citations , December 1998 in “The journal of investigative dermatology/Journal of investigative dermatology”

Hair follicle melanocytes die during hair regression.

research From neural crest cells to melanocytes: cellular plasticity during development and beyond

66 citations , March 2019 in “Cellular and Molecular Life Sciences”

Melanocyte development from neural crest cells is complex and influenced by many factors, and better understanding could help treat skin disorders.

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